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FMDV replicons encoding green fluorescent protein are replication competent.
Tulloch F, Pathania U, Luke GA, Nicholson J, Stonehouse NJ, Rowlands DJ, Jackson T, Tuthill T, Haas J, Lamond AI, Ryan MD. Tulloch F, et al. Among authors: tuthill t. J Virol Methods. 2014 Dec;209:35-40. doi: 10.1016/j.jviromet.2014.08.020. Epub 2014 Sep 4. J Virol Methods. 2014. PMID: 25194890 Free PMC article.
Mutagenesis Mapping of RNA Structures within the Foot-and-Mouth Disease Virus Genome Reveals Functional Elements Localized in the Polymerase (3Dpol)-Encoding Region.
Lasecka-Dykes L, Tulloch F, Simmonds P, Luke GA, Ribeca P, Gold S, Knowles NJ, Wright CF, Wadsworth J, Azhar M, King DP, Tuthill TJ, Jackson T, Ryan MD. Lasecka-Dykes L, et al. Among authors: tuthill tj. mSphere. 2021 Aug 25;6(4):e0001521. doi: 10.1128/mSphere.00015-21. Epub 2021 Jul 14. mSphere. 2021. PMID: 34259558 Free PMC article.
The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication, but essential for the production of infectious virus.
Ward JC, Lasecka-Dykes L, Neil C, Adeyemi OO, Gold S, McLean-Pell N, Wright C, Herod MR, Kealy D, Warner E, Jackson T, King DP, Tuthill TJ, Rowlands DJ, Stonehouse NJ. Ward JC, et al. Among authors: tuthill tj. PLoS Pathog. 2022 Jun 6;18(6):e1010589. doi: 10.1371/journal.ppat.1010589. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35666744 Free PMC article.
Picornaviruses.
Tuthill TJ, Groppelli E, Hogle JM, Rowlands DJ. Tuthill TJ, et al. Curr Top Microbiol Immunol. 2010;343:43-89. doi: 10.1007/82_2010_37. Curr Top Microbiol Immunol. 2010. PMID: 20397067 Free PMC article.
94 results