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The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension.
Chen J, Tang H, Sysol JR, Moreno-Vinasco L, Shioura KM, Chen T, Gorshkova I, Wang L, Huang LS, Usatyuk PV, Sammani S, Zhou G, Raj JU, Garcia JG, Berdyshev E, Yuan JX, Natarajan V, Machado RF. Chen J, et al. Among authors: gorshkova i. Am J Respir Crit Care Med. 2014 Nov 1;190(9):1032-43. doi: 10.1164/rccm.201401-0121OC. Am J Respir Crit Care Med. 2014. PMID: 25180446 Free PMC article.
Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1.
Zhao Y, Kalari SK, Usatyuk PV, Gorshkova I, He D, Watkins T, Brindley DN, Sun C, Bittman R, Garcia JG, Berdyshev EV, Natarajan V. Zhao Y, et al. Among authors: gorshkova i. J Biol Chem. 2007 May 11;282(19):14165-77. doi: 10.1074/jbc.M701279200. Epub 2007 Mar 22. J Biol Chem. 2007. PMID: 17379599 Free PMC article.
Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
Gorshkova I, Zhou T, Mathew B, Jacobson JR, Takekoshi D, Bhattacharya P, Smith B, Aydogan B, Weichselbaum RR, Natarajan V, Garcia JG, Berdyshev EV. Gorshkova I, et al. J Lipid Res. 2012 Aug;53(8):1553-68. doi: 10.1194/jlr.M026039. Epub 2012 May 21. J Lipid Res. 2012. PMID: 22615416 Free PMC article.
Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins.
Harijith A, Pendyala S, Reddy NM, Bai T, Usatyuk PV, Berdyshev E, Gorshkova I, Huang LS, Mohan V, Garzon S, Kanteti P, Reddy SP, Raj JU, Natarajan V. Harijith A, et al. Among authors: gorshkova i. Am J Pathol. 2013 Oct;183(4):1169-1182. doi: 10.1016/j.ajpath.2013.06.018. Epub 2013 Aug 8. Am J Pathol. 2013. PMID: 23933064 Free PMC article.
130 results