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The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension.
Chen J, Tang H, Sysol JR, Moreno-Vinasco L, Shioura KM, Chen T, Gorshkova I, Wang L, Huang LS, Usatyuk PV, Sammani S, Zhou G, Raj JU, Garcia JG, Berdyshev E, Yuan JX, Natarajan V, Machado RF. Chen J, et al. Among authors: berdyshev e. Am J Respir Crit Care Med. 2014 Nov 1;190(9):1032-43. doi: 10.1164/rccm.201401-0121OC. Am J Respir Crit Care Med. 2014. PMID: 25180446 Free PMC article.
Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
Gorshkova I, Zhou T, Mathew B, Jacobson JR, Takekoshi D, Bhattacharya P, Smith B, Aydogan B, Weichselbaum RR, Natarajan V, Garcia JG, Berdyshev EV. Gorshkova I, et al. J Lipid Res. 2012 Aug;53(8):1553-68. doi: 10.1194/jlr.M026039. Epub 2012 May 21. J Lipid Res. 2012. PMID: 22615416 Free PMC article.
Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.
Mathew B, Jacobson JR, Berdyshev E, Huang Y, Sun X, Zhao Y, Gerhold LM, Siegler J, Evenoski C, Wang T, Zhou T, Zaidi R, Moreno-Vinasco L, Bittman R, Chen CT, LaRiviere PJ, Sammani S, Lussier YA, Dudek SM, Natarajan V, Weichselbaum RR, Garcia JG. Mathew B, et al. Among authors: berdyshev e. FASEB J. 2011 Oct;25(10):3388-400. doi: 10.1096/fj.11-183970. Epub 2011 Jun 28. FASEB J. 2011. PMID: 21712494 Free PMC article.
Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis.
Huang LS, Berdyshev E, Mathew B, Fu P, Gorshkova IA, He D, Ma W, Noth I, Ma SF, Pendyala S, Reddy SP, Zhou T, Zhang W, Garzon SA, Garcia JG, Natarajan V. Huang LS, et al. Among authors: berdyshev e. FASEB J. 2013 Apr;27(4):1749-60. doi: 10.1096/fj.12-219634. Epub 2013 Jan 11. FASEB J. 2013. PMID: 23315259 Free PMC article.
Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.
Natarajan V, Dudek SM, Jacobson JR, Moreno-Vinasco L, Huang LS, Abassi T, Mathew B, Zhao Y, Wang L, Bittman R, Weichselbaum R, Berdyshev E, Garcia JG. Natarajan V, et al. Among authors: berdyshev e. Am J Respir Cell Mol Biol. 2013 Jul;49(1):6-17. doi: 10.1165/rcmb.2012-0411TR. Am J Respir Cell Mol Biol. 2013. PMID: 23449739 Free PMC article. Review.
Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins.
Harijith A, Pendyala S, Reddy NM, Bai T, Usatyuk PV, Berdyshev E, Gorshkova I, Huang LS, Mohan V, Garzon S, Kanteti P, Reddy SP, Raj JU, Natarajan V. Harijith A, et al. Among authors: berdyshev e. Am J Pathol. 2013 Oct;183(4):1169-1182. doi: 10.1016/j.ajpath.2013.06.018. Epub 2013 Aug 8. Am J Pathol. 2013. PMID: 23933064 Free PMC article.
Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation.
Park GY, Lee YG, Berdyshev E, Nyenhuis S, Du J, Fu P, Gorshkova IA, Li Y, Chung S, Karpurapu M, Deng J, Ranjan R, Xiao L, Jaffe HA, Corbridge SJ, Kelly EA, Jarjour NN, Chun J, Prestwich GD, Kaffe E, Ninou I, Aidinis V, Morris AJ, Smyth SS, Ackerman SJ, Natarajan V, Christman JW. Park GY, et al. Among authors: berdyshev e. Am J Respir Crit Care Med. 2013 Oct 15;188(8):928-40. doi: 10.1164/rccm.201306-1014OC. Am J Respir Crit Care Med. 2013. PMID: 24050723 Free PMC article.
139 results