Abrams CS - Search Results

1

Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice.

Min SH, Suzuki A, Stalker TJ, Zhao L, Wang Y, McKennan C, Riese MJ, Guzman JF, Zhang S, Lian L, Joshi R, Meng R, Seeholzer SH, Choi JK, Koretzky G, Marks MS, Abrams CS. Min SH, et al. Among authors: abrams cs. Nat Commun. 2014 Sep 2;5:4691. doi: 10.1038/ncomms5691. Nat Commun. 2014. PMID: 25178411 Free PMC article.

2

Membrane grease eases platelet maturation.

Min SH, Abrams CS. Min SH, et al. Among authors: abrams cs. Blood. 2015 Aug 27;126(9):1055-6. doi: 10.1182/blood-2015-07-655241. Blood. 2015. PMID: 26316615 Free PMC article.

3

Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis.

Zhao L, Thorsheim CL, Suzuki A, Stalker TJ, Min SH, Lian L, Fairn GD, Cockcroft S, Durham A, Krishnaswamy S, Abrams CS. Zhao L, et al. Among authors: abrams cs. Nat Commun. 2017 Oct 31;8(1):1216. doi: 10.1038/s41467-017-01181-4. Nat Commun. 2017. PMID: 29084966 Free PMC article.

4

PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice.

Min SH, Suzuki A, Weaver L, Guzman J, Chung Y, Jin H, Gonzalez F, Trasorras C, Zhao L, Spruce LA, Seeholzer SH, Behrens EM, Abrams CS. Min SH, et al. Among authors: abrams cs. Mol Cell Biol. 2019 Oct 11;39(21):e00158-19. doi: 10.1128/MCB.00158-19. Print 2019 Nov 1. Mol Cell Biol. 2019. PMID: 31427458 Free PMC article.

5

Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.

Wang Y, Chen X, Lian L, Tang T, Stalker TJ, Sasaki T, Kanaho Y, Brass LF, Choi JK, Hartwig JH, Abrams CS. Wang Y, et al. Among authors: abrams cs. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14064-9. doi: 10.1073/pnas.0804139105. Epub 2008 Sep 4. Proc Natl Acad Sci U S A. 2008. PMID: 18772378 Free PMC article.

6

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis.

Lian L, Wang Y, Flick M, Choi J, Scott EW, Degen J, Lemmon MA, Abrams CS. Lian L, et al. Among authors: abrams cs. Blood. 2009 Apr 9;113(15):3577-84. doi: 10.1182/blood-2008-09-178913. Epub 2009 Feb 3. Blood. 2009. PMID: 19190246 Free PMC article.

7

Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction.

Wang Y, Meng R, Hayes V, Fuentes R, Yu X, Abrams CS, Heijnen HF, Blobel GA, Marks MS, Poncz M. Wang Y, et al. Among authors: abrams cs. Blood. 2011 Dec 1;118(23):6183-91. doi: 10.1182/blood-2011-06-363580. Epub 2011 Oct 11. Blood. 2011. PMID: 21989988 Free PMC article.

8

Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion.

Wang Y, Zhao L, Suzuki A, Lian L, Min SH, Wang Z, Litvinov RI, Stalker TJ, Yago T, Klopocki AG, Schmidtke DW, Yin H, Choi JK, McEver RP, Weisel JW, Hartwig JH, Abrams CS. Wang Y, et al. Among authors: abrams cs. Blood. 2013 Apr 4;121(14):2743-52. doi: 10.1182/blood-2012-07-445205. Epub 2013 Jan 31. Blood. 2013. PMID: 23372168 Free PMC article.

9

Regulation of platelet plug formation by phosphoinositide metabolism.

Min SH, Abrams CS. Min SH, et al. Among authors: abrams cs. Blood. 2013 Aug 22;122(8):1358-65. doi: 10.1182/blood-2013-05-427716. Epub 2013 Jun 11. Blood. 2013. PMID: 23757731 Free PMC article. Review.

10

RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation.

Suzuki A, Shin JW, Wang Y, Min SH, Poncz M, Choi JK, Discher DE, Carpenter CL, Lian L, Zhao L, Wang Y, Abrams CS. Suzuki A, et al. Among authors: abrams cs. PLoS One. 2013 Jul 23;8(7):e69315. doi: 10.1371/journal.pone.0069315. Print 2013. PLoS One. 2013. PMID: 23935982 Free PMC article.

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