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VEGF secreted by hypoxic Müller cells induces MMP-2 expression and activity in endothelial cells to promote retinal neovascularization in proliferative diabetic retinopathy.
Rodrigues M, Xin X, Jee K, Babapoor-Farrokhran S, Kashiwabuchi F, Ma T, Bhutto I, Hassan SJ, Daoud Y, Baranano D, Solomon S, Lutty G, Semenza GL, Montaner S, Sodhi A. Rodrigues M, et al. Among authors: sodhi a. Diabetes. 2013 Nov;62(11):3863-73. doi: 10.2337/db13-0014. Epub 2013 Jul 24. Diabetes. 2013. PMID: 23884892 Free PMC article.
Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.
Xin X, Rodrigues M, Umapathi M, Kashiwabuchi F, Ma T, Babapoor-Farrokhran S, Wang S, Hu J, Bhutto I, Welsbie DS, Duh EJ, Handa JT, Eberhart CG, Lutty G, Semenza GL, Montaner S, Sodhi A. Xin X, et al. Among authors: sodhi a. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3425-34. doi: 10.1073/pnas.1217091110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959876 Free PMC article.
Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma.
Hu K, Babapoor-Farrokhran S, Rodrigues M, Deshpande M, Puchner B, Kashiwabuchi F, Hassan SJ, Asnaghi L, Handa JT, Merbs S, Eberhart CG, Semenza GL, Montaner S, Sodhi A. Hu K, et al. Among authors: sodhi a. Oncotarget. 2016 Feb 16;7(7):7816-28. doi: 10.18632/oncotarget.6868. Oncotarget. 2016. PMID: 26761211 Free PMC article.
Pro-permeability Factors in Diabetic Macular Edema; the Diabetic Macular Edema Treated With Ozurdex Trial.
Campochiaro PA, Hafiz G, Mir TA, Scott AW, Zimmer-Galler I, Shah SM, Wenick AS, Brady CJ, Han I, He L, Channa R, Poon D, Meyerle C, Aronow MB, Sodhi A, Handa JT, Kherani S, Han Y, Sophie R, Wang G, Qian J. Campochiaro PA, et al. Among authors: sodhi a. Am J Ophthalmol. 2016 Aug;168:13-23. doi: 10.1016/j.ajo.2016.04.017. Epub 2016 Apr 27. Am J Ophthalmol. 2016. PMID: 27130369 Free PMC article. Clinical Trial.
Reply.
Campochiaro PA, Hafiz G, Mir TA, Scott AW, Zimmer-Galler I, Shah SM, Wenick AS, Brady CJ, Han I, He L, Channa R, Poon D, Meyerle C, Aronow MB, Sodhi A, Handa JT, Kherani S, Han Y, Sophie R, Wang G, Qian J. Campochiaro PA, et al. Among authors: sodhi a. Am J Ophthalmol. 2016 Oct;170:245-246. doi: 10.1016/j.ajo.2016.07.014. Epub 2016 Aug 22. Am J Ophthalmol. 2016. PMID: 27561424 No abstract available.
291 results