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Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation.
Bunda S, Heir P, Srikumar T, Cook JD, Burrell K, Kano Y, Lee JE, Zadeh G, Raught B, Ohh M. Bunda S, et al. Among authors: kano y. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3785-94. doi: 10.1073/pnas.1406559111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157176 Free PMC article.
The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors.
Gebregiworgis T, Kano Y, St-Germain J, Radulovich N, Udaskin ML, Mentes A, Huang R, Poon BPK, He W, Valencia-Sama I, Robinson CM, Huestis M, Miao J, Yeh JJ, Zhang ZY, Irwin MS, Lee JE, Tsao MS, Raught B, Marshall CB, Ohh M, Ikura M. Gebregiworgis T, et al. Among authors: kano y. Nat Commun. 2021 Nov 1;12(1):6274. doi: 10.1038/s41467-021-26526-y. Nat Commun. 2021. PMID: 34725361 Free PMC article.
Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line.
Fukushima K, Tsuchiya K, Kano Y, Horita N, Hibiya S, Hayashi R, Kitagaki K, Negi M, Itoh E, Akashi T, Eishi Y, Oshima S, Nagaishi T, Okamoto R, Nakamura T, Watanabe M. Fukushima K, et al. Among authors: kano y. Cancer Sci. 2015 Aug;106(8):1000-7. doi: 10.1111/cas.12703. Epub 2015 Jul 14. Cancer Sci. 2015. PMID: 26017781 Free PMC article.
Protocol for the nationwide registry of patients with polycystic kidney disease: japanese national registry of PKD (JRP).
Nakatani S, Kawano H, Sato M, Hoshino J, Nishio S, Miura K, Sekine A, Suwabe T, Hidaka S, Kataoka H, Ishikawa E, Shimazu K, Uchiyama K, Fujimaru T, Moriyama T, Kurashige M, Shimabukuro W, Hattanda F, Kimura T, Ushio Y, Manabe S, Watanabe H, Mitobe M, Seta K, Shimada Y, Kai H, Katayama K, Ichikawa D, Hayashi H, Hanaoka K, Mochizuki T, Nakanishi K, Tsuchiya K, Horie S, Isaka Y, Muto S; JRP collaborators. Nakatani S, et al. Clin Exp Nephrol. 2024 May 11. doi: 10.1007/s10157-024-02509-3. Online ahead of print. Clin Exp Nephrol. 2024. PMID: 38734869
1,167 results