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Human papillomavirus type 1 E1^E4 protein is a potent inhibitor of the serine-arginine (SR) protein kinase SRPK1 and inhibits phosphorylation of host SR proteins and of the viral transcription and replication regulator E2.
Prescott EL, Brimacombe CL, Hartley M, Bell I, Graham S, Roberts S. Prescott EL, et al. Among authors: roberts s. J Virol. 2014 Nov;88(21):12599-611. doi: 10.1128/JVI.02029-14. Epub 2014 Aug 20. J Virol. 2014. PMID: 25142587 Free PMC article.
A cyclin-binding motif in human papillomavirus type 18 (HPV18) E1^E4 is necessary for association with CDK-cyclin complexes and G2/M cell cycle arrest of keratinocytes, but is not required for differentiation-dependent viral genome amplification or L1 capsid protein expression.
Knight GL, Pugh AG, Yates E, Bell I, Wilson R, Moody CA, Laimins LA, Roberts S. Knight GL, et al. Among authors: roberts s. Virology. 2011 Mar 30;412(1):196-210. doi: 10.1016/j.virol.2011.01.007. Epub 2011 Jan 31. Virology. 2011. PMID: 21276999 Free PMC article.
5,828 results