Humanin antagonists: mutants that interfere with dimerization inhibit neuroprotection by Humanin.
Hashimoto Y, Terashita K, Niikura T, Yamagishi Y, Ishizaka M, Kanekura K, Chiba T, Yamada M, Kita Y, Aiso S, Matsuoka M, Nishimoto I.
Hashimoto Y, et al.
Eur J Neurosci. 2004 May;19(9):2356-64. doi: 10.1111/j.0953-816X.2004.03298.x.
Eur J Neurosci. 2004.
PMID: 15128389
We have previously shown that P3A, S7A, C8A, L9A, L12A, T13A, S14A and P19A mutations nullify the neuroprotective function of HN [Yamagishi, Y., Hashimoto, Y., Niikura, T. & Nishimoto, I. (2003) Peptides, 24, 585-595]. ...
We have previously shown that P3A, S7A, C8A, L9A, L12A, T13A, S14A and P19A mutations nullify the neuroprotective function of HN [Yamagishi, …