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An investigation of targeted inhibition of transcription factor activity with pyrrole imidazole polyamide (PA) in chronic myeloid leukemia (CML) blast crisis cells.
Hayatigolkhatmi K, Padroni G, Su W, Fang L, Gómez-Castañeda E, Hsieh YC, Jackson L, Pellicano F, Burley GA, Jørgensen HG. Hayatigolkhatmi K, et al. Among authors: padroni g. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2622-2625. doi: 10.1016/j.bmcl.2019.07.049. Epub 2019 Jul 27. Bioorg Med Chem Lett. 2019. PMID: 31378570 Free article.
Investigation of a minor groove-binding polyamide targeted to E2F1 transcription factor in chronic myeloid leukaemia (CML) cells.
Hayatigolkhatmi K, Padroni G, Su W, Fang L, Gómez-Castañeda E, Hsieh YC, Jackson L, Holyoake TL, Pellicano F, Burley GA, Jørgensen HG. Hayatigolkhatmi K, et al. Among authors: padroni g. Blood Cells Mol Dis. 2018 Mar;69:119-122. doi: 10.1016/j.bcmd.2017.11.002. Epub 2017 Nov 26. Blood Cells Mol Dis. 2018. PMID: 29217295 Free article. No abstract available.
Specific protein-RNA interactions are mostly preserved in biomolecular condensates.
de Vries T, Novakovic M, Ni Y, Smok I, Inghelram C, Bikaki M, Sarnowski CP, Han Y, Emmanouilidis L, Padroni G, Leitner A, Allain FH. de Vries T, et al. Among authors: padroni g. Sci Adv. 2024 Mar 8;10(10):eadm7435. doi: 10.1126/sciadv.adm7435. Epub 2024 Mar 6. Sci Adv. 2024. PMID: 38446881 Free PMC article.
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