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Transcriptional and epigenetic networks of helper T and innate lymphoid cells.
Shih HY, Sciumè G, Poholek AC, Vahedi G, Hirahara K, Villarino AV, Bonelli M, Bosselut R, Kanno Y, Muljo SA, O'Shea JJ. Shih HY, et al. Among authors: poholek ac. Immunol Rev. 2014 Sep;261(1):23-49. doi: 10.1111/imr.12208. Immunol Rev. 2014. PMID: 25123275 Free PMC article. Review.
Distinct requirements for T-bet in gut innate lymphoid cells.
Sciumé G, Hirahara K, Takahashi H, Laurence A, Villarino AV, Singleton KL, Spencer SP, Wilhelm C, Poholek AC, Vahedi G, Kanno Y, Belkaid Y, O'Shea JJ. Sciumé G, et al. Among authors: poholek ac. J Exp Med. 2012 Dec 17;209(13):2331-8. doi: 10.1084/jem.20122097. Epub 2012 Dec 3. J Exp Med. 2012. PMID: 23209316 Free PMC article.
Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program.
Nakayamada S, Poholek AC, Lu KT, Takahashi H, Kato M, Iwata S, Hirahara K, Cannons JL, Schwartzberg PL, Vahedi G, Sun HW, Kanno Y, O'Shea JJ. Nakayamada S, et al. Among authors: poholek ac. J Immunol. 2014 Mar 1;192(5):2156-66. doi: 10.4049/jimmunol.1300675. Epub 2014 Jan 31. J Immunol. 2014. PMID: 24489092 Free PMC article.
IL-10 induces a STAT3-dependent autoregulatory loop in TH2 cells that promotes Blimp-1 restriction of cell expansion via antagonism of STAT5 target genes.
Poholek AC, Jankovic D, Villarino AV, Petermann F, Hettinga A, Shouval DS, Snapper SB, Kaech SM, Brooks SR, Vahedi G, Sher A, Kanno Y, O'Shea JJ. Poholek AC, et al. Sci Immunol. 2016 Oct;1(5):eaaf8612. doi: 10.1126/sciimmunol.aaf8612. Epub 2016 Nov 11. Sci Immunol. 2016. PMID: 28713870 Free PMC article.
MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23.
Mikami Y, Philips RL, Sciumè G, Petermann F, Meylan F, Nagashima H, Yao C, Davis FP, Brooks SR, Sun HW, Takahashi H, Poholek AC, Shih HY, Afzali B, Muljo SA, Hafner M, Kanno Y, O'Shea JJ. Mikami Y, et al. Among authors: poholek ac. Immunity. 2021 Mar 9;54(3):514-525.e6. doi: 10.1016/j.immuni.2021.02.015. Epub 2021 Mar 2. Immunity. 2021. PMID: 33657395 Free PMC article.
CD4 T follicular helper cell dynamics during SIV infection.
Petrovas C, Yamamoto T, Gerner MY, Boswell KL, Wloka K, Smith EC, Ambrozak DR, Sandler NG, Timmer KJ, Sun X, Pan L, Poholek A, Rao SS, Brenchley JM, Alam SM, Tomaras GD, Roederer M, Douek DC, Seder RA, Germain RN, Haddad EK, Koup RA. Petrovas C, et al. J Clin Invest. 2012 Sep;122(9):3281-94. doi: 10.1172/JCI63039. Epub 2012 Aug 27. J Clin Invest. 2012. PMID: 22922258 Free PMC article.
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion.
Sawant DV, Yano H, Chikina M, Zhang Q, Liao M, Liu C, Callahan DJ, Sun Z, Sun T, Tabib T, Pennathur A, Corry DB, Luketich JD, Lafyatis R, Chen W, Poholek AC, Bruno TC, Workman CJ, Vignali DAA. Sawant DV, et al. Among authors: poholek ac. Nat Immunol. 2019 Jun;20(6):724-735. doi: 10.1038/s41590-019-0346-9. Epub 2019 Apr 1. Nat Immunol. 2019. PMID: 30936494 Free PMC article.
44 results