Yadav V - Search Results

1

The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation.

Yadav V, Burke TF, Huber L, Van Horn RD, Zhang Y, Buchanan SG, Chan EM, Starling JJ, Beckmann RP, Peng SB. Yadav V, et al. Mol Cancer Ther. 2014 Oct;13(10):2253-63. doi: 10.1158/1535-7163.MCT-14-0257. Epub 2014 Aug 13. Mol Cancer Ther. 2014. PMID: 25122067

2

Reactivation of mitogen-activated protein kinase (MAPK) pathway by FGF receptor 3 (FGFR3)/Ras mediates resistance to vemurafenib in human B-RAF V600E mutant melanoma.

Yadav V, Zhang X, Liu J, Estrem S, Li S, Gong XQ, Buchanan S, Henry JR, Starling JJ, Peng SB. Yadav V, et al. J Biol Chem. 2012 Aug 10;287(33):28087-98. doi: 10.1074/jbc.M112.377218. Epub 2012 Jun 22. J Biol Chem. 2012. PMID: 22730329 Free PMC article.

3

Co-targeting BRAF and cyclin dependent kinases 4/6 for BRAF mutant cancers.

Yadav V, Chen SH, Yue YG, Buchanan S, Beckmann RP, Peng SB. Yadav V, et al. Pharmacol Ther. 2015 May;149:139-49. doi: 10.1016/j.pharmthera.2014.12.003. Epub 2014 Dec 27. Pharmacol Ther. 2015. PMID: 25550229 Review.

4

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.

Peng SB, Henry JR, Kaufman MD, Lu WP, Smith BD, Vogeti S, Rutkoski TJ, Wise S, Chun L, Zhang Y, Van Horn RD, Yin T, Zhang X, Yadav V, Chen SH, Gong X, Ma X, Webster Y, Buchanan S, Mochalkin I, Huber L, Kays L, Donoho GP, Walgren J, McCann D, Patel P, Conti I, Plowman GD, Starling JJ, Flynn DL. Peng SB, et al. Among authors: yadav v. Cancer Cell. 2015 Sep 14;28(3):384-98. doi: 10.1016/j.ccell.2015.08.002. Epub 2015 Sep 3. Cancer Cell. 2015. PMID: 26343583 Free article.

5

Oncogenic BRAF Deletions That Function as Homodimers and Are Sensitive to Inhibition by RAF Dimer Inhibitor LY3009120.

Chen SH, Zhang Y, Van Horn RD, Yin T, Buchanan S, Yadav V, Mochalkin I, Wong SS, Yue YG, Huber L, Conti I, Henry JR, Starling JJ, Plowman GD, Peng SB. Chen SH, et al. Among authors: yadav v. Cancer Discov. 2016 Mar;6(3):300-15. doi: 10.1158/2159-8290.CD-15-0896. Epub 2016 Jan 5. Cancer Discov. 2016. PMID: 26732095

6

Identification of druggable cancer driver genes amplified across TCGA datasets.

Chen Y, McGee J, Chen X, Doman TN, Gong X, Zhang Y, Hamm N, Ma X, Higgs RE, Bhagwat SV, Buchanan S, Peng SB, Staschke KA, Yadav V, Yue Y, Kouros-Mehr H. Chen Y, et al. Among authors: yadav v. PLoS One. 2014 May 29;9(5):e98293. doi: 10.1371/journal.pone.0098293. eCollection 2014. PLoS One. 2014. PMID: 24874471 Free PMC article.

7

Activating the Wnt/β-Catenin Pathway for the Treatment of Melanoma--Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3.

Atkinson JM, Rank KB, Zeng Y, Capen A, Yadav V, Manro JR, Engler TA, Chedid M. Atkinson JM, et al. Among authors: yadav v. PLoS One. 2015 Apr 27;10(4):e0125028. doi: 10.1371/journal.pone.0125028. eCollection 2015. PLoS One. 2015. PMID: 25915038 Free PMC article.

8

Functional alterations in protein kinase C beta II expression in melanoma.

Voris JP, Sitailo LA, Rahn HR, Defnet A, Gerds AT, Sprague R, Yadav V, Caroline Le Poole I, Denning MF. Voris JP, et al. Among authors: yadav v. Pigment Cell Melanoma Res. 2010 Apr;23(2):216-24. doi: 10.1111/j.1755-148X.2009.00664.x. Epub 2009 Dec 14. Pigment Cell Melanoma Res. 2010. PMID: 20015121

9

Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration.

Yadav V, Denning MF. Yadav V, et al. Mol Carcinog. 2011 May;50(5):346-52. doi: 10.1002/mc.20716. Epub 2010 Dec 10. Mol Carcinog. 2011. PMID: 21480388 Free PMC article.

10

Prevalence of non-communicable chronic diseases in rural India amongst peri- and post-menopausal women: Can artificial intelligence help in early identification?

Shah D, Yadav V, Singh UP, Sinha A, Dumka N, Banerjee R, Shah R, Unni J, Manneni VR. Shah D, et al. Among authors: yadav v. Maturitas. 2024 May 16:108029. doi: 10.1016/j.maturitas.2024.108029. Online ahead of print. Maturitas. 2024. PMID: 38816334

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