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Page 1
DNA methylation markers for early detection of women's cancer: promise and challenges.
Wittenberger T, Sleigh S, Reisel D, Zikan M, Wahl B, Alunni-Fabbroni M, Jones A, Evans I, Koch J, Paprotka T, Lempiäinen H, Rujan T, Rack B, Cibula D, Widschwendter M. Wittenberger T, et al. Among authors: lempiainen h. Epigenomics. 2014 Jun;6(3):311-27. doi: 10.2217/epi.14.20. Epigenomics. 2014. PMID: 25111485 Review.
Methylation patterns in serum DNA for early identification of disseminated breast cancer.
Widschwendter M, Evans I, Jones A, Ghazali S, Reisel D, Ryan A, Gentry-Maharaj A, Zikan M, Cibula D, Eichner J, Alunni-Fabbroni M, Koch J, Janni WJ, Paprotka T, Wittenberger T, Menon U, Wahl B, Rack B, Lempiäinen H. Widschwendter M, et al. Among authors: lempiainen h. Genome Med. 2017 Dec 22;9(1):115. doi: 10.1186/s13073-017-0499-9. Genome Med. 2017. PMID: 29268762 Free PMC article. Clinical Trial.
The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer.
Widschwendter M, Zikan M, Wahl B, Lempiäinen H, Paprotka T, Evans I, Jones A, Ghazali S, Reisel D, Eichner J, Rujan T, Yang Z, Teschendorff AE, Ryan A, Cibula D, Menon U, Wittenberger T. Widschwendter M, et al. Among authors: lempiainen h. Genome Med. 2017 Dec 22;9(1):116. doi: 10.1186/s13073-017-0500-7. Genome Med. 2017. PMID: 29268796 Free PMC article.
Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets.
Lempiäinen H, Brænne I, Michoel T, Tragante V, Vilne B, Webb TR, Kyriakou T, Eichner J, Zeng L, Willenborg C, Franzen O, Ruusalepp A, Goel A, van der Laan SW, Biegert C, Hamby S, Talukdar HA, Foroughi Asl H; CVgenes@target consortium; Pasterkamp G, Watkins H, Samani NJ, Wittenberger T, Erdmann J, Schunkert H, Asselbergs FW, Björkegren JLM. Lempiäinen H, et al. Sci Rep. 2018 Feb 21;8(1):3434. doi: 10.1038/s41598-018-20721-6. Sci Rep. 2018. PMID: 29467471 Free PMC article.
Druggability of Coronary Artery Disease Risk Loci.
Tragante V, Hemerich D, Alshabeeb M, Brænne I, Lempiäinen H, Patel RS, den Ruijter HM, Barnes MR, Moore JH, Schunkert H, Erdmann J, Asselbergs FW. Tragante V, et al. Among authors: lempiainen h. Circ Genom Precis Med. 2018 Aug;11(8):e001977. doi: 10.1161/CIRCGEN.117.001977. Circ Genom Precis Med. 2018. PMID: 30354342 Free PMC article.
Ha-ras and β-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors.
Unterberger EB, Eichner J, Wrzodek C, Lempiäinen H, Luisier R, Terranova R, Metzger U, Plummer S, Knorpp T, Braeuning A, Moggs J, Templin MF, Honndorf V, Piotto M, Zell A, Schwarz M. Unterberger EB, et al. Among authors: lempiainen h. Int J Cancer. 2014 Oct 1;135(7):1574-85. doi: 10.1002/ijc.28798. Epub 2014 Mar 3. Int J Cancer. 2014. PMID: 24535843 Free article.
Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion.
Lempiäinen H, Couttet P, Bolognani F, Müller A, Dubost V, Luisier R, Del Rio Espinola A, Vitry V, Unterberger EB, Thomson JP, Treindl F, Metzger U, Wrzodek C, Hahne F, Zollinger T, Brasa S, Kalteis M, Marcellin M, Giudicelli F, Braeuning A, Morawiec L, Zamurovic N, Längle U, Scheer N, Schübeler D, Goodman J, Chibout SD, Marlowe J, Theil D, Heard DJ, Grenet O, Zell A, Templin MF, Meehan RR, Wolf RC, Elcombe CR, Schwarz M, Moulin P, Terranova R, Moggs JG. Lempiäinen H, et al. Toxicol Sci. 2013 Feb;131(2):375-86. doi: 10.1093/toxsci/kfs303. Epub 2012 Oct 22. Toxicol Sci. 2013. PMID: 23091169
Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.
Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth RS, Webb S, Kerr AR, Lyall MJ, Drake AJ, Wolf CR, Moggs JG, Schwarz M, Meehan RR. Thomson JP, et al. Among authors: lempiainen h. Cancer Res. 2016 May 15;76(10):3097-108. doi: 10.1158/0008-5472.CAN-15-1910. Epub 2016 Apr 6. Cancer Res. 2016. PMID: 27197233 Free PMC article.
Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, Grasl-Kraupp B, Ellinger-Ziegelbauer H, Thomson JP, Meehan RR, Elcombe CR, Henderson CJ, Wolf CR, Schwarz M, Moulin P, Terranova R, Moggs JG. Luisier R, et al. Among authors: lempiainen h. Toxicol Sci. 2014 Jun;139(2):501-11. doi: 10.1093/toxsci/kfu038. Epub 2014 Apr 1. Toxicol Sci. 2014. PMID: 24690595
19 results