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The leukemogenicity of Hoxa9 depends on alternative splicing.
Stadler CR, Vegi N, Mulaw MA, Edmaier KE, Rawat VP, Dolnik A, Bullinger L, Heilmeier B, Quintanilla-Fend L, Spiekermann K, Hiddemann W, Döhner K, Döhner H, Feuring-Buske M, Buske C. Stadler CR, et al. Among authors: edmaier ke. Leukemia. 2014 Sep;28(9):1838-43. doi: 10.1038/leu.2014.74. Epub 2014 Feb 18. Leukemia. 2014. PMID: 24535405
High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia.
Metzeler KH, Heilmeier B, Edmaier KE, Rawat VP, Dufour A, Döhner K, Feuring-Buske M, Braess J, Spiekermann K, Büchner T, Sauerland MC, Döhner H, Hiddemann W, Bohlander SK, Schlenk RF, Bullinger L, Buske C. Metzeler KH, et al. Among authors: edmaier ke. Blood. 2012 Sep 6;120(10):2118-26. doi: 10.1182/blood-2012-02-411827. Epub 2012 Jul 18. Blood. 2012. PMID: 22815426 Free article.