Saleh AF - Search Results

1

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model.

Bestas B, Moreno PM, Blomberg KE, Mohammad DK, Saleh AF, Sutlu T, Nordin JZ, Guterstam P, Gustafsson MO, Kharazi S, Piątosa B, Roberts TC, Behlke MA, Wood MJ, Gait MJ, Lundin KE, El Andaloussi S, Månsson R, Berglöf A, Wengel J, Smith CI. Bestas B, et al. Among authors: saleh af. J Clin Invest. 2014 Sep;124(9):4067-81. doi: 10.1172/JCI76175. Epub 2014 Aug 8. J Clin Invest. 2014. PMID: 25105368 Free PMC article.

2

Peptide nanoparticle delivery of charge-neutral splice-switching morpholino oligonucleotides.

Järver P, Zaghloul EM, Arzumanov AA, Saleh AF, McClorey G, Hammond SM, Hällbrink M, Langel Ü, Smith CI, Wood MJ, Gait MJ, El Andaloussi S. Järver P, et al. Among authors: saleh af. Nucleic Acid Ther. 2015 Apr;25(2):65-77. doi: 10.1089/nat.2014.0511. Epub 2015 Jan 16. Nucleic Acid Ther. 2015. PMID: 25594433 Free PMC article.

3

Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy.

Shabanpoor F, McClorey G, Saleh AF, Järver P, Wood MJ, Gait MJ. Shabanpoor F, et al. Among authors: saleh af. Nucleic Acids Res. 2015 Jan;43(1):29-39. doi: 10.1093/nar/gku1256. Epub 2014 Dec 2. Nucleic Acids Res. 2015. PMID: 25468897 Free PMC article.

4

Optimization of peptide nucleic acid antisense oligonucleotides for local and systemic dystrophin splice correction in the mdx mouse.

Yin H, Betts C, Saleh AF, Ivanova GD, Lee H, Seow Y, Kim D, Gait MJ, Wood MJ. Yin H, et al. Among authors: saleh af. Mol Ther. 2010 Apr;18(4):819-27. doi: 10.1038/mt.2009.310. Epub 2010 Jan 12. Mol Ther. 2010. PMID: 20068555 Free PMC article.

5

In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy.

Wang Q, Yin H, Camelliti P, Betts C, Moulton H, Lee H, Saleh AF, Gait MJ, Wood MJ. Wang Q, et al. Among authors: saleh af. J Gene Med. 2010 Apr;12(4):354-64. doi: 10.1002/jgm.1446. J Gene Med. 2010. PMID: 20235089

6

Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides.

Ezzat K, Aoki Y, Koo T, McClorey G, Benner L, Coenen-Stass A, O'Donovan L, Lehto T, Garcia-Guerra A, Nordin J, Saleh AF, Behlke M, Morris J, Goyenvalle A, Dugovic B, Leumann C, Gordon S, Gait MJ, El-Andaloussi S, Wood MJ. Ezzat K, et al. Among authors: saleh af. Nano Lett. 2015 Jul 8;15(7):4364-73. doi: 10.1021/acs.nanolett.5b00490. Epub 2015 Jun 15. Nano Lett. 2015. PMID: 26042553 Free PMC article.

7

Splice redirection as a convenient assay to monitor CPP-ON efficiency and mechanism.

Abes R, Arzumanov AA, Saleh AF, Said Hassane F, Gait MJ, Lebleu B. Abes R, et al. Among authors: saleh af. Methods Mol Biol. 2011;683:307-20. doi: 10.1007/978-1-60761-919-2_22. Methods Mol Biol. 2011. PMID: 21053139

8

Overview of alternative oligonucleotide chemistries for exon skipping.

Saleh AF, Arzumanov AA, Gait MJ. Saleh AF, et al. Methods Mol Biol. 2012;867:365-78. doi: 10.1007/978-1-61779-767-5_23. Methods Mol Biol. 2012. PMID: 22454073 Review.

9

Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics.

Coenen-Stass AM, McClorey G, Manzano R, Betts CA, Blain A, Saleh AF, Gait MJ, Lochmüller H, Wood MJ, Roberts TC. Coenen-Stass AM, et al. Among authors: saleh af. Sci Rep. 2015 Nov 23;5:17014. doi: 10.1038/srep17014. Sci Rep. 2015. PMID: 26594036 Free PMC article.

10

Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy.

Hammond SM, Hazell G, Shabanpoor F, Saleh AF, Bowerman M, Sleigh JN, Meijboom KE, Zhou H, Muntoni F, Talbot K, Gait MJ, Wood MJ. Hammond SM, et al. Among authors: saleh af. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10962-7. doi: 10.1073/pnas.1605731113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621445 Free PMC article.

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