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ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.
Agnihotri S, Burrell K, Buczkowicz P, Remke M, Golbourn B, Chornenkyy Y, Gajadhar A, Fernandez NA, Clarke ID, Barszczyk MS, Pajovic S, Ternamian C, Head R, Sabha N, Sobol RW, Taylor MD, Rutka JT, Jones C, Dirks PB, Zadeh G, Hawkins C. Agnihotri S, et al. Among authors: sobol rw. Cancer Discov. 2014 Oct;4(10):1198-213. doi: 10.1158/2159-8290.CD-14-0157. Epub 2014 Aug 6. Cancer Discov. 2014. PMID: 25100205 Free PMC article.
Targeting DNA polymerase ß for therapeutic intervention.
Goellner EM, Svilar D, Almeida KH, Sobol RW. Goellner EM, et al. Among authors: sobol rw. Curr Mol Pharmacol. 2012 Jan;5(1):68-87. Curr Mol Pharmacol. 2012. PMID: 22122465 Free PMC article. Review.
Alkylation sensitivity screens reveal a conserved cross-species functionome.
Svilar D, Dyavaiah M, Brown AR, Tang JB, Li J, McDonald PR, Shun TY, Braganza A, Wang XH, Maniar S, St Croix CM, Lazo JS, Pollack IF, Begley TJ, Sobol RW. Svilar D, et al. Among authors: sobol rw. Mol Cancer Res. 2012 Dec;10(12):1580-96. doi: 10.1158/1541-7786.MCR-12-0168. Epub 2012 Oct 4. Mol Cancer Res. 2012. PMID: 23038810 Free PMC article.
Synthesis and characterization of DNA minor groove binding alkylating agents.
Iyer P, Srinivasan A, Singh SK, Mascara GP, Zayitova S, Sidone B, Fouquerel E, Svilar D, Sobol RW, Bobola MS, Silber JR, Gold B. Iyer P, et al. Among authors: sobol rw. Chem Res Toxicol. 2013 Jan 18;26(1):156-68. doi: 10.1021/tx300437x. Epub 2012 Dec 26. Chem Res Toxicol. 2013. PMID: 23234400 Free PMC article.
148 results