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ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.
Agnihotri S, Burrell K, Buczkowicz P, Remke M, Golbourn B, Chornenkyy Y, Gajadhar A, Fernandez NA, Clarke ID, Barszczyk MS, Pajovic S, Ternamian C, Head R, Sabha N, Sobol RW, Taylor MD, Rutka JT, Jones C, Dirks PB, Zadeh G, Hawkins C. Agnihotri S, et al. Among authors: gajadhar a. Cancer Discov. 2014 Oct;4(10):1198-213. doi: 10.1158/2159-8290.CD-14-0157. Epub 2014 Aug 6. Cancer Discov. 2014. PMID: 25100205 Free PMC article.
Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.
Agnihotri S, Gajadhar AS, Ternamian C, Gorlia T, Diefes KL, Mischel PS, Kelly J, McGown G, Thorncroft M, Carlson BL, Sarkaria JN, Margison GP, Aldape K, Hawkins C, Hegi M, Guha A. Agnihotri S, et al. Among authors: gajadhar as. J Clin Invest. 2012 Jan;122(1):253-66. doi: 10.1172/JCI59334. Epub 2011 Dec 12. J Clin Invest. 2012. PMID: 22156195 Free PMC article.
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas.
Agnihotri S, Wolf A, Munoz DM, Smith CJ, Gajadhar A, Restrepo A, Clarke ID, Fuller GN, Kesari S, Dirks PB, McGlade CJ, Stanford WL, Aldape K, Mischel PS, Hawkins C, Guha A. Agnihotri S, et al. Among authors: gajadhar a. J Exp Med. 2011 Apr 11;208(4):689-702. doi: 10.1084/jem.20102099. Epub 2011 Apr 4. J Exp Med. 2011. PMID: 21464220 Free PMC article.
Proteomics: present and future implications in neuro-oncology.
Micallef J, Gajadhar A, Wiley J, DeSouza LV, Michael Siu KW, Guha A. Micallef J, et al. Among authors: gajadhar a. Neurosurgery. 2008 Mar;62(3):539-55; discussion 539-55. doi: 10.1227/01.neu.0000317302.85837.61. Neurosurgery. 2008. PMID: 18425004 Review.
Phosphotyrosine signaling analysis in human tumors is confounded by systemic ischemia-driven artifacts and intra-specimen heterogeneity.
Gajadhar AS, Johnson H, Slebos RJ, Shaddox K, Wiles K, Washington MK, Herline AJ, Levine DA, Liebler DC, White FM; Clinical Proteomic Tumor Analysis Consortium. Gajadhar AS, et al. Cancer Res. 2015 Apr 1;75(7):1495-503. doi: 10.1158/0008-5472.CAN-14-2309. Epub 2015 Feb 10. Cancer Res. 2015. PMID: 25670172 Free PMC article.
System level dynamics of post-translational modifications.
Gajadhar AS, White FM. Gajadhar AS, et al. Curr Opin Biotechnol. 2014 Aug;28:83-7. doi: 10.1016/j.copbio.2013.12.009. Epub 2014 Jan 15. Curr Opin Biotechnol. 2014. PMID: 24441143 Free PMC article. Review.
155 results