Ford L - Search Results

1

Discovery and in vivo evaluation of alcohol-containing benzothiazoles as potent dual-targeting bacterial DNA supercoiling inhibitors.

Palmer JT, Axford LC, Barker S, Bennett JM, Blair M, Collins I, Davies DT, Ford L, Gannon CT, Lancett P, Logan A, Lunniss CJ, Morton CJ, Offermann DA, Pitt GR, Rao BN, Singh AK, Shukla T, Srivastava A, Stokes NR, Thomaides-Brears HB, Yadav A, Haydon DJ. Palmer JT, et al. Among authors: ford l. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4215-22. doi: 10.1016/j.bmcl.2014.07.037. Epub 2014 Jul 19. Bioorg Med Chem Lett. 2014. PMID: 25086682

2

A Structure-Activity Relationship Study of Bitopic N⁶-Substituted Adenosine Derivatives as Biased Adenosine A₁ Receptor Agonists.

Aurelio L, Baltos JA, Ford L, Nguyen ATN, Jörg M, Devine SM, Valant C, White PJ, Christopoulos A, May LT, Scammells PJ. Aurelio L, et al. Among authors: ford l. J Med Chem. 2018 Mar 8;61(5):2087-2103. doi: 10.1021/acs.jmedchem.8b00047. Epub 2018 Feb 23. J Med Chem. 2018. PMID: 29446948

3

Cyclosporin Structure and Permeability: From A to Z and Beyond.

Corbett KM, Ford L, Warren DB, Pouton CW, Chalmers DK. Corbett KM, et al. Among authors: ford l. J Med Chem. 2021 Sep 23;64(18):13131-13151. doi: 10.1021/acs.jmedchem.1c00580. Epub 2021 Sep 3. J Med Chem. 2021. PMID: 34478303 Review.

4

The hybrid molecule, VCP746, is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling.

Vecchio EA, Chuo CH, Baltos JA, Ford L, Scammells PJ, Wang BH, Christopoulos A, White PJ, May LT. Vecchio EA, et al. Among authors: ford l. Biochem Pharmacol. 2016 Oct 1;117:46-56. doi: 10.1016/j.bcp.2016.08.007. Epub 2016 Aug 9. Biochem Pharmacol. 2016. PMID: 27520486

5

Ionic liquids provide unique opportunities for oral drug delivery: structure optimization and in vivo evidence of utility.

Williams HD, Sahbaz Y, Ford L, Nguyen TH, Scammells PJ, Porter CJ. Williams HD, et al. Among authors: ford l. Chem Commun (Camb). 2014 Feb 18;50(14):1688-90. doi: 10.1039/c3cc48650h. Chem Commun (Camb). 2014. PMID: 24394756

6

Transformation of poorly water-soluble drugs into lipophilic ionic liquids enhances oral drug exposure from lipid based formulations.

Sahbaz Y, Williams HD, Nguyen TH, Saunders J, Ford L, Charman SA, Scammells PJ, Porter CJ. Sahbaz Y, et al. Among authors: ford l. Mol Pharm. 2015 Jun 1;12(6):1980-91. doi: 10.1021/mp500790t. Epub 2015 May 5. Mol Pharm. 2015. PMID: 25905624

7

Ionic Liquid Forms of Weakly Acidic Drugs in Oral Lipid Formulations: Preparation, Characterization, in Vitro Digestion, and in Vivo Absorption Studies.

Sahbaz Y, Nguyen TH, Ford L, McEvoy CL, Williams HD, Scammells PJ, Porter CJH. Sahbaz Y, et al. Among authors: ford l. Mol Pharm. 2017 Nov 6;14(11):3669-3683. doi: 10.1021/acs.molpharmaceut.7b00442. Epub 2017 Oct 10. Mol Pharm. 2017. PMID: 28954512

8

Ionic Liquid Forms of the Antimalarial Lumefantrine in Combination with LFCS Type IIIB Lipid-Based Formulations Preferentially Increase Lipid Solubility, In Vitro Solubilization Behavior and In Vivo Exposure.

Tay E, Nguyen TH, Ford L, Williams HD, Benameur H, Scammells PJ, Porter CJH. Tay E, et al. Among authors: ford l. Pharmaceutics. 2019 Dec 22;12(1):17. doi: 10.3390/pharmaceutics12010017. Pharmaceutics. 2019. PMID: 31877828 Free PMC article.

9

API ionic liquids: probing the effect of counterion structure on physical form and lipid solubility.

Ford L, Tay E, Nguyen TH, Williams HD, Benameur H, Scammells PJ, Porter CJH. Ford L, et al. RSC Adv. 2020 Mar 31;10(22):12788-12799. doi: 10.1039/d0ra00386g. eCollection 2020 Mar 30. RSC Adv. 2020. PMID: 35492138 Free PMC article.

10

Stabilising disproportionation of lipophilic ionic liquid salts in lipid-based formulations.

Lai A, Sahbaz Y, Ford L, Nguyen TH, Haque S, Williams HD, Benameur H, Scammells PJ, Porter CJH. Lai A, et al. Among authors: ford l. Int J Pharm. 2021 Mar 15;597:120292. doi: 10.1016/j.ijpharm.2021.120292. Epub 2021 Feb 11. Int J Pharm. 2021. PMID: 33581479

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