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Facile entry to an efficient and practical enantioselective synthesis of a polycyclic cholesteryl ester transfer protein inhibitor.
Han ZS, Xu Y, Fandrick DR, Rodriguez S, Li Z, Qu B, Gonnella NC, Sanyal S, Reeves JT, Ma S, Grinberg N, Haddad N, Krishnamurthy D, Song JJ, Yee NK, Pfrengle W, Ostermeier M, Schnaubelt J, Leuter Z, Steigmiller S, Däubler J, Stehle E, Neumann L, Trieselmann T, Tielmann P, Buba A, Hamm R, Koch G, Renner S, Dehli JR, Schmelcher F, Stange C, Mack J, Soyka R, Senanayake CH. Han ZS, et al. Among authors: schnaubelt j. Org Lett. 2014 Aug 15;16(16):4142-5. doi: 10.1021/ol501833g. Epub 2014 Aug 1. Org Lett. 2014. PMID: 25084526
Synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid vinyl-ACCA) derivatives: key intermediates for the preparation of inhibitors of the hepatitis C virus NS3 protease.
Beaulieu PL, Gillard J, Bailey MD, Boucher C, Duceppe JS, Simoneau B, Wang XJ, Zhang L, Grozinger K, Houpis I, Farina V, Heimroth H, Krueger T, Schnaubelt J. Beaulieu PL, et al. Among authors: schnaubelt j. J Org Chem. 2005 Jul 22;70(15):5869-79. doi: 10.1021/jo050468q. J Org Chem. 2005. PMID: 16018680
Total synthesis of rapamycin.
Ley SV, Tackett MN, Maddess ML, Anderson JC, Brennan PE, Cappi MW, Heer JP, Helgen C, Kori M, Kouklovsky C, Marsden SP, Norman J, Osborn DP, Palomero MA, Pavey JB, Pinel C, Robinson LA, Schnaubelt J, Scott JS, Spilling CD, Watanabe H, Wesson KE, Willis MC. Ley SV, et al. Among authors: schnaubelt j. Chemistry. 2009;15(12):2874-914. doi: 10.1002/chem.200801656. Chemistry. 2009. PMID: 19204960