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Facile entry to an efficient and practical enantioselective synthesis of a polycyclic cholesteryl ester transfer protein inhibitor.
Han ZS, Xu Y, Fandrick DR, Rodriguez S, Li Z, Qu B, Gonnella NC, Sanyal S, Reeves JT, Ma S, Grinberg N, Haddad N, Krishnamurthy D, Song JJ, Yee NK, Pfrengle W, Ostermeier M, Schnaubelt J, Leuter Z, Steigmiller S, Däubler J, Stehle E, Neumann L, Trieselmann T, Tielmann P, Buba A, Hamm R, Koch G, Renner S, Dehli JR, Schmelcher F, Stange C, Mack J, Soyka R, Senanayake CH. Han ZS, et al. Among authors: li z. Org Lett. 2014 Aug 15;16(16):4142-5. doi: 10.1021/ol501833g. Epub 2014 Aug 1. Org Lett. 2014. PMID: 25084526
Asymmetric hydrogenation of unsaturated ureas with the BIPI ligands.
Busacca CA, Lorenz JC, Grinberg N, Haddad N, Lee H, Li Z, Liang M, Reeves D, Saha A, Varsolona R, Senanayake CH. Busacca CA, et al. Among authors: li z. Org Lett. 2008 Jan 17;10(2):341-4. doi: 10.1021/ol7028542. Epub 2007 Dec 21. Org Lett. 2008. PMID: 18095698
Efficient asymmetric synthesis of P-chiral phosphine oxides via properly designed and activated benzoxazaphosphinine-2-oxide agents.
Han ZS, Goyal N, Herbage MA, Sieber JD, Qu B, Xu Y, Li Z, Reeves JT, Desrosiers JN, Ma S, Grinberg N, Lee H, Mangunuru HP, Zhang Y, Krishnamurthy D, Lu BZ, Song JJ, Wang G, Senanayake CH. Han ZS, et al. Among authors: li z. J Am Chem Soc. 2013 Feb 20;135(7):2474-7. doi: 10.1021/ja312352p. Epub 2013 Feb 6. J Am Chem Soc. 2013. PMID: 23369026
[2,3]-Sigmatropic rearrangements of 2-phosphineborane 2-propen-1-ols: rapid access to enantioenriched diphosphine monoxide derivatives.
Busacca CA, Qu B, Farber E, Haddad N, Grět N, Saha AK, Eriksson MC, Wu JP, Fandrick KR, Han S, Grinberg N, Ma S, Lee H, Li Z, Spinelli M, Gold A, Wang Z, Wang G, Wipf P, Senanayake CH. Busacca CA, et al. Among authors: li z. Org Lett. 2013 Mar 1;15(5):1136-9. doi: 10.1021/ol400310h. Epub 2013 Feb 21. Org Lett. 2013. PMID: 23427861
Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.
Reeves JT, Fandrick DR, Tan Z, Song JJ, Rodriguez S, Qu B, Kim S, Niemeier O, Li Z, Byrne D, Campbell S, Chitroda A, DeCroos P, Fachinger T, Fuchs V, Gonnella NC, Grinberg N, Haddad N, Jäger B, Lee H, Lorenz JC, Ma S, Narayanan BA, Nummy LJ, Premasiri A, Roschangar F, Sarvestani M, Shen S, Spinelli E, Sun X, Varsolona RJ, Yee N, Brenner M, Senanayake CH. Reeves JT, et al. Among authors: li z. J Org Chem. 2013 Apr 19;78(8):3616-35. doi: 10.1021/jo400079z. Epub 2013 Apr 1. J Org Chem. 2013. PMID: 23544738
Development of an asymmetric synthesis of a chiral quaternary FLAP inhibitor.
Fandrick KR, Mulder JA, Patel ND, Gao J, Konrad M, Archer E, Buono FG, Duran A, Schmid R, Daeubler J, Desrosiers JN, Zeng X, Rodriguez S, Ma S, Qu B, Li Z, Fandrick DR, Grinberg N, Lee H, Bosanac T, Takahashi H, Chen Z, Bartolozzi A, Nemoto P, Busacca CA, Song JJ, Yee NK, Mahaney PE, Senanayake CH. Fandrick KR, et al. Among authors: li z. J Org Chem. 2015 Feb 6;80(3):1651-60. doi: 10.1021/jo502550h. Epub 2015 Jan 22. J Org Chem. 2015. PMID: 25562342
Diastereoselective Synthesis of α-Quaternary Aziridine-2-carboxylates via Aza-Corey-Chaykovsky Aziridination of N-tert-Butanesulfinyl Ketimino Esters.
Marsini MA, Reeves JT, Desrosiers JN, Herbage MA, Savoie J, Li Z, Fandrick KR, Sader CA, McKibben B, Gao DA, Cui J, Gonnella NC, Lee H, Wei X, Roschangar F, Lu BZ, Senanayake CH. Marsini MA, et al. Among authors: li z. Org Lett. 2015 Nov 20;17(22):5614-7. doi: 10.1021/acs.orglett.5b02838. Epub 2015 Nov 11. Org Lett. 2015. PMID: 26558319
Hydrophosphination of propargylic alcohols and amines with phosphine boranes.
Busacca CA, Qu B, Farber E, Haddad N, Grět N, Saha AK, Eriksson MC, Wu JP, Fandrick KR, Han S, Grinberg N, Ma S, Lee H, Li Z, Spinelli M, Gold A, Wang G, Wipf P, Senanayake CH. Busacca CA, et al. Among authors: li z. Org Lett. 2013 Mar 1;15(5):1132-5. doi: 10.1021/ol400309y. Epub 2013 Feb 21. Org Lett. 2013. PMID: 23427869
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