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Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD.
Mizumura K, Cloonan SM, Nakahira K, Bhashyam AR, Cervo M, Kitada T, Glass K, Owen CA, Mahmood A, Washko GR, Hashimoto S, Ryter SW, Choi AM. Mizumura K, et al. Among authors: owen ca. J Clin Invest. 2014 Sep;124(9):3987-4003. doi: 10.1172/JCI74985. Epub 2014 Aug 1. J Clin Invest. 2014. PMID: 25083992 Free PMC article.
Genetically manipulated mouse models of lung disease: potential and pitfalls.
Baron RM, Choi AJ, Owen CA, Choi AM. Baron RM, et al. Among authors: owen ca. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15;302(6):L485-97. doi: 10.1152/ajplung.00085.2011. Epub 2011 Dec 23. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22198907 Free PMC article. Review.
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.
Lam HC, Cloonan SM, Bhashyam AR, Haspel JA, Singh A, Sathirapongsasuti JF, Cervo M, Yao H, Chung AL, Mizumura K, An CH, Shan B, Franks JM, Haley KJ, Owen CA, Tesfaigzi Y, Washko GR, Quackenbush J, Silverman EK, Rahman I, Kim HP, Mahmood A, Biswal SS, Ryter SW, Choi AM. Lam HC, et al. Among authors: owen ca. J Clin Invest. 2013 Dec;123(12):5212-30. doi: 10.1172/JCI69636. Epub 2013 Nov 8. J Clin Invest. 2013. PMID: 24200693 Free PMC article.
Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.
Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM. Cloonan SM, et al. Among authors: owen ca. Nat Med. 2016 Feb;22(2):163-74. doi: 10.1038/nm.4021. Epub 2016 Jan 11. Nat Med. 2016. PMID: 26752519 Free PMC article.
A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin.
Jiang Z, Lao T, Qiu W, Polverino F, Gupta K, Guo F, Mancini JD, Naing ZZ, Cho MH, Castaldi PJ, Sun Y, Yu J, Laucho-Contreras ME, Kobzik L, Raby BA, Choi AM, Perrella MA, Owen CA, Silverman EK, Zhou X. Jiang Z, et al. Among authors: owen ca. Am J Respir Crit Care Med. 2016 Jul 15;194(2):185-97. doi: 10.1164/rccm.201505-0999OC. Am J Respir Crit Care Med. 2016. PMID: 26862784 Free PMC article.
Transcriptomic Analysis of Lung Tissue from Cigarette Smoke-Induced Emphysema Murine Models and Human Chronic Obstructive Pulmonary Disease Show Shared and Distinct Pathways.
Yun JH, Morrow J, Owen CA, Qiu W, Glass K, Lao T, Jiang Z, Perrella MA, Silverman EK, Zhou X, Hersh CP. Yun JH, et al. Among authors: owen ca. Am J Respir Cell Mol Biol. 2017 Jul;57(1):47-58. doi: 10.1165/rcmb.2016-0328OC. Am J Respir Cell Mol Biol. 2017. PMID: 28248572 Free PMC article.
Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease.
Pabón MA, Patino E, Bhatia D, Rojas-Quintero J, Ma KC, Finkelsztein EJ, Osorio JC, Malick F, Polverino F, Owen CA, Ryter SW, Choi AM, Cloonan SM, Choi ME. Pabón MA, et al. Among authors: owen ca. JCI Insight. 2018 Sep 20;3(18):e99592. doi: 10.1172/jci.insight.99592. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232271 Free PMC article.
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.
Lam HC, Cloonan SM, Bhashyam AR, Haspel JA, Singh A, Sathirapongsasuti JF, Cervo M, Yao H, Chung AL, Mizumura K, An CH, Shan B, Franks JM, Haley KJ, Owen CA, Tesfaigzi Y, Washko GR, Quackenbush J, Silverman EK, Rahman I, Kim HP, Mahmood A, Biswal SS, Ryter SW, Choi AM. Lam HC, et al. Among authors: owen ca. J Clin Invest. 2020 Nov 2;130(11):6189. doi: 10.1172/JCI143863. J Clin Invest. 2020. PMID: 33136096 Free PMC article. No abstract available.
503 results