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Increasing FIM2/3 antigen-content improves efficacy of Bordetella pertussis vaccines in mice in vivo without altering vaccine-induced human reactogenicity biomarkers in vitro.
Queenan AM, Dowling DJ, Cheng WK, Faé K, Fernandez J, Flynn PJ, Joshi S, Brightman SE, Ramirez J, Serroyen J, Wiertsema S, Fortanier A, van den Dobbelsteen G, Levy O, Poolman J. Queenan AM, et al. Vaccine. 2019 Jan 3;37(1):80-89. doi: 10.1016/j.vaccine.2018.11.028. Epub 2018 Nov 23. Vaccine. 2019. PMID: 30478007 Free PMC article.
Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial.
Huttner A, Hatz C, van den Dobbelsteen G, Abbanat D, Hornacek A, Frölich R, Dreyer AM, Martin P, Davies T, Fae K, van den Nieuwenhof I, Thoelen S, de Vallière S, Kuhn A, Bernasconi E, Viereck V, Kavvadias T, Kling K, Ryu G, Hülder T, Gröger S, Scheiner D, Alaimo C, Harbarth S, Poolman J, Fonck VG. Huttner A, et al. Lancet Infect Dis. 2017 May;17(5):528-537. doi: 10.1016/S1473-3099(17)30108-1. Epub 2017 Feb 24. Lancet Infect Dis. 2017. PMID: 28238601 Clinical Trial.
Resurgence of pertussis calls for re-evaluation of pertussis animal models.
van der Ark AA, Hozbor DF, Boog CJ, Metz B, van den Dobbelsteen GP, van Els CA. van der Ark AA, et al. Among authors: van den dobbelsteen gp, van els ca. Expert Rev Vaccines. 2012 Sep;11(9):1121-37. doi: 10.1586/erv.12.83. Expert Rev Vaccines. 2012. PMID: 23151168 Review.
73 results