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Many forks in the path: cycling with FoxO.
Ho KK, Myatt SS, Lam EW. Ho KK, et al. Among authors: lam ew. Oncogene. 2008 Apr 7;27(16):2300-11. doi: 10.1038/onc.2008.23. Oncogene. 2008. PMID: 18391972 Review.
The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression.
Hui RC, Gomes AR, Constantinidou D, Costa JR, Karadedou CT, Fernandez de Mattos S, Wymann MP, Brosens JJ, Schulze A, Lam EW. Hui RC, et al. Among authors: lam ew. Mol Cell Biol. 2008 Oct;28(19):5886-98. doi: 10.1128/MCB.01265-07. Epub 2008 Jul 21. Mol Cell Biol. 2008. PMID: 18644865 Free PMC article.
Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer.
McGovern UB, Francis RE, Peck B, Guest SK, Wang J, Myatt SS, Krol J, Kwok JM, Polychronis A, Coombes RC, Lam EW. McGovern UB, et al. Among authors: lam ew. Mol Cancer Ther. 2009 Mar;8(3):582-91. doi: 10.1158/1535-7163.MCT-08-0805. Epub 2009 Mar 10. Mol Cancer Ther. 2009. PMID: 19276163 Free article.
FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer.
Francis RE, Myatt SS, Krol J, Hartman J, Peck B, McGovern UB, Wang J, Guest SK, Filipovic A, Gojis O, Palmieri C, Peston D, Shousha S, Yu Q, Sicinski P, Coombes RC, Lam EW. Francis RE, et al. Among authors: lam ew. Int J Oncol. 2009 Jul;35(1):57-68. doi: 10.3892/ijo_00000313. Int J Oncol. 2009. PMID: 19513552 Free PMC article.
369 results