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Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects.
Wang CQ, Krishnan V, Tay LS, Chin DW, Koh CP, Chooi JY, Nah GS, Du L, Jacob B, Yamashita N, Lai SK, Tan TZ, Mori S, Tanuichi I, Tergaonkar V, Ito Y, Osato M. Wang CQ, et al. Among authors: du l. Cell Rep. 2014 Aug 7;8(3):767-82. doi: 10.1016/j.celrep.2014.06.046. Epub 2014 Jul 24. Cell Rep. 2014. PMID: 25066130 Free article.
Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells.
Koh CP, Bahirvani AG, Wang CQ, Yokomizo T, Ng CEL, Du L, Tergaonkar V, Voon DC, Kitamura H, Hosoi H, Sonoki T, Michelle MMH, Tan LJ, Niibori-Nambu A, Zhang Y, Perkins AS, Hossain Z, Tenen DG, Ito Y, Venkatesh B, Osato M. Koh CP, et al. Among authors: du l. Gene. 2023 Jan 30;851:147049. doi: 10.1016/j.gene.2022.147049. Epub 2022 Nov 13. Gene. 2023. PMID: 36384171 Free PMC article.
7,604 results