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Maintenance of adult cardiac function requires the chromatin factor Asxl2.
Lai HL, Grachoff M, McGinley AL, Khan FF, Warren CM, Chowdhury SA, Wolska BM, Solaro RJ, Geenen DL, Wang QT. Lai HL, et al. Among authors: wang qt. J Mol Cell Cardiol. 2012 Nov;53(5):734-41. doi: 10.1016/j.yjmcc.2012.08.014. Epub 2012 Aug 27. J Mol Cell Cardiol. 2012. PMID: 23046516 Free PMC article.
ASXL2 Regulates Glucose, Lipid, and Skeletal Homeostasis.
Izawa T, Rohatgi N, Fukunaga T, Wang QT, Silva MJ, Gardner MJ, McDaniel ML, Abumrad NA, Semenkovich CF, Teitelbaum SL, Zou W. Izawa T, et al. Among authors: wang qt. Cell Rep. 2015 Jun 16;11(10):1625-37. doi: 10.1016/j.celrep.2015.05.019. Epub 2015 Jun 4. Cell Rep. 2015. PMID: 26051940 Free PMC article.
Loss of Asxl2 leads to myeloid malignancies in mice.
Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Guo Y, Yang H, Man N, Greenblatt S, Li Z, Guo Z, Zhou Y, Wang L, Morey L, Williams S, Chen X, Wang QT, Nimer SD, Yu P, Wang QF, Xu M, Yang FC. Li J, et al. Among authors: wang l, wang qt, wang qf. Nat Commun. 2017 Jun 8;8:15456. doi: 10.1038/ncomms15456. Nat Commun. 2017. PMID: 28593990 Free PMC article.
ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion.
Madan V, Han L, Hattori N, Teoh WW, Mayakonda A, Sun QY, Ding LW, Nordin HBM, Lim SL, Shyamsunder P, Dakle P, Sundaresan J, Doan NB, Sanada M, Sato-Otsubo A, Meggendorfer M, Yang H, Said JW, Ogawa S, Haferlach T, Liang DC, Shih LY, Nakamaki T, Wang QT, Koeffler HP. Madan V, et al. Among authors: wang qt. Haematologica. 2018 Dec;103(12):1980-1990. doi: 10.3324/haematol.2018.189928. Epub 2018 Aug 9. Haematologica. 2018. PMID: 30093396 Free PMC article.
177 results