Parkinson JA - Search Results

1

Recognition of the DNA minor groove by thiazotropsin analogues.

Alniss HY, Salvia MV, Sadikov M, Golovchenko I, Anthony NG, Khalaf AI, MacKay SP, Suckling CJ, Parkinson JA. Alniss HY, et al. Among authors: parkinson ja. Chembiochem. 2014 Sep 5;15(13):1978-90. doi: 10.1002/cbic.201402202. Epub 2014 Jul 16. Chembiochem. 2014. PMID: 25045155

2

Minor-groove recognition of the self-complementary duplex d(CGCGAATTCGCG)2 by Hoechst 33258: a high-field NMR study.

Parkinson JA, Barber J, Douglas KT, Rosamond J, Sharples D. Parkinson JA, et al. Biochemistry. 1990 Nov 6;29(44):10181-90. doi: 10.1021/bi00496a005. Biochemistry. 1990. PMID: 1703003

3

Predictability of designing specific binding interactions for DNA minor groove ligands from NMR spectroscopy and molecular modeling: a copper(II)-activated DNA cleaver based on Hoechst 33258.

Parkinson J, Sadat-Ebrahimi S, Wilton A, McKie JH, Andrews J, Douglas KT. Parkinson J, et al. Biochemistry. 1995 Dec 19;34(50):16240-4. doi: 10.1021/bi00050a002. Biochemistry. 1995. PMID: 8845347

4

DNA binding of a short lexitropsin.

Anthony NG, Fox KR, Johnston BF, Khalaf AI, Mackay SP, McGroarty IS, Parkinson JA, Skellern GG, Suckling CJ, Waigh RD. Anthony NG, et al. Among authors: parkinson ja. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1353-6. doi: 10.1016/j.bmcl.2003.11.068. Bioorg Med Chem Lett. 2004. PMID: 14980697

5

Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole.

Anthony NG, Johnston BF, Khalaf AI, MacKay SP, Parkinson JA, Suckling CJ, Waigh RD. Anthony NG, et al. Among authors: parkinson ja. J Am Chem Soc. 2004 Sep 15;126(36):11338-49. doi: 10.1021/ja030658n. J Am Chem Soc. 2004. PMID: 15355117

6

In silico footprinting of ligands binding to the minor groove of DNA.

Anthony NG, Huchet G, Johnston BF, Parkinson JA, Suckling CJ, Waigh RD, Mackay SP. Anthony NG, et al. Among authors: parkinson ja. J Chem Inf Model. 2005 Nov-Dec;45(6):1896-907. doi: 10.1021/ci050153b. J Chem Inf Model. 2005. PMID: 16309297

7

Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups.

Anthony NG, Breen D, Clarke J, Donoghue G, Drummond AJ, Ellis EM, Gemmell CG, Helesbeux JJ, Hunter IS, Khalaf AI, Mackay SP, Parkinson JA, Suckling CJ, Waigh RD. Anthony NG, et al. Among authors: parkinson ja. J Med Chem. 2007 Nov 29;50(24):6116-25. doi: 10.1021/jm070831g. Epub 2007 Oct 26. J Med Chem. 2007. PMID: 17960927

8

A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity.

Anthony NG, Breen D, Donoghue G, Khalaf AI, Mackay SP, Parkinson JA, Suckling CJ. Anthony NG, et al. Among authors: parkinson ja. Org Biomol Chem. 2009 May 7;7(9):1843-50. doi: 10.1039/b901898k. Epub 2009 Mar 12. Org Biomol Chem. 2009. PMID: 19590779

9

A detailed binding free energy study of 2:1 ligand-DNA complex formation by experiment and simulation.

Treesuwan W, Wittayanarakul K, Anthony NG, Huchet G, Alniss H, Hannongbua S, Khalaf AI, Suckling CJ, Parkinson JA, Mackay SP. Treesuwan W, et al. Among authors: parkinson ja. Phys Chem Chem Phys. 2009 Dec 7;11(45):10682-93. doi: 10.1039/b910574c. Epub 2009 Sep 22. Phys Chem Chem Phys. 2009. PMID: 20145812 Free article.

10

Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove.

Salvia MV, Addison F, Alniss HY, Buurma NJ, Khalaf AI, Mackay SP, Anthony NG, Suckling CJ, Evstigneev MP, Santiago AH, Waigh RD, Parkinson JA. Salvia MV, et al. Among authors: parkinson ja. Biophys Chem. 2013 Sep;179:1-11. doi: 10.1016/j.bpc.2013.04.001. Epub 2013 Apr 25. Biophys Chem. 2013. PMID: 23714424 Free article.

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