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A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation.
Schmitz AL, Schrage R, Gaffal E, Charpentier TH, Wiest J, Hiltensperger G, Morschel J, Hennen S, Häußler D, Horn V, Wenzel D, Grundmann M, Büllesbach KM, Schröder R, Brewitz HH, Schmidt J, Gomeza J, Galés C, Fleischmann BK, Tüting T, Imhof D, Tietze D, Gütschow M, Holzgrabe U, Sondek J, Harden TK, Mohr K, Kostenis E. Schmitz AL, et al. Among authors: imhof d. Chem Biol. 2014 Jul 17;21(7):890-902. doi: 10.1016/j.chembiol.2014.06.003. Chem Biol. 2014. PMID: 25036778 Free PMC article.
Revealing the position of the substrate in nickel superoxide dismutase: a model study.
Tietze D, Voigt S, Mollenhauer D, Tischler M, Imhof D, Gutmann T, González L, Ohlenschläger O, Breitzke H, Görlach M, Buntkowsky G. Tietze D, et al. Among authors: imhof d. Angew Chem Int Ed Engl. 2011 Mar 21;50(13):2946-50. doi: 10.1002/anie.201005027. Epub 2011 Feb 25. Angew Chem Int Ed Engl. 2011. PMID: 21404375 No abstract available.
Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4.
Tietze AA, Tietze D, Ohlenschläger O, Leipold E, Ullrich F, Kühl T, Mischo A, Buntkowsky G, Görlach M, Heinemann SH, Imhof D. Tietze AA, et al. Among authors: imhof d. Angew Chem Int Ed Engl. 2012 Apr 23;51(17):4058-61. doi: 10.1002/anie.201107011. Epub 2012 Mar 12. Angew Chem Int Ed Engl. 2012. PMID: 22407516 Review. No abstract available.
The experimental power of FR900359 to study Gq-regulated biological processes.
Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, Charpentier TH, Martz M, Butcher AJ, Slodczyk T, Armando S, Effern M, Namkung Y, Jenkins L, Horn V, Stößel A, Dargatz H, Tietze D, Imhof D, Galés C, Drewke C, Müller CE, Hölzel M, Milligan G, Tobin AB, Gomeza J, Dohlman HG, Sondek J, Harden TK, Bouvier M, Laporte SA, Aoki J, Fleischmann BK, Mohr K, König GM, Tüting T, Kostenis E. Schrage R, et al. Among authors: imhof d. Nat Commun. 2015 Dec 14;6:10156. doi: 10.1038/ncomms10156. Nat Commun. 2015. PMID: 26658454 Free PMC article.
Molecular interaction of δ-conopeptide EVIA with voltage-gated Na(+) channels.
Tietze D, Leipold E, Heimer P, Böhm M, Winschel W, Imhof D, Heinemann SH, Tietze AA. Tietze D, et al. Among authors: imhof d. Biochim Biophys Acta. 2016 Sep;1860(9):2053-63. doi: 10.1016/j.bbagen.2016.06.013. Epub 2016 Jun 15. Biochim Biophys Acta. 2016. PMID: 27316322 No abstract available.
138 results