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The structure of DarB in complex with RelNTD reveals nonribosomal activation of Rel stringent factors.
Ainelo A, Caballero-Montes J, Bulvas O, Ernits K, Coppieters 't Wallant K, Takada H, Craig SZ, Mazzucchelli G, Zedek S, Pichová I, Atkinson GC, Talavera A, Martens C, Hauryliuk V, Garcia-Pino A. Ainelo A, et al. Among authors: mazzucchelli g. Sci Adv. 2023 Jan 18;9(3):eade4077. doi: 10.1126/sciadv.ade4077. Epub 2023 Jan 18. Sci Adv. 2023. PMID: 36652515 Free PMC article.
Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation.
Papadopoulos N, Nédélec A, Derenne A, Şulea TA, Pecquet C, Chachoua I, Vertenoeil G, Tilmant T, Petrescu AJ, Mazzucchelli G, Iorga BI, Vertommen D, Constantinescu SN. Papadopoulos N, et al. Among authors: mazzucchelli g. Nat Commun. 2023 Apr 5;14(1):1881. doi: 10.1038/s41467-023-37277-3. Nat Commun. 2023. PMID: 37019903 Free PMC article.
Discovery of a natural thiamine adenine nucleotide.
Bettendorff L, Wirtzfeld B, Makarchikov AF, Mazzucchelli G, Frédérich M, Gigliobianco T, Gangolf M, De Pauw E, Angenot L, Wins P. Bettendorff L, et al. Among authors: mazzucchelli g. Nat Chem Biol. 2007 Apr;3(4):211-2. doi: 10.1038/nchembio867. Epub 2007 Mar 4. Nat Chem Biol. 2007. PMID: 17334376 Free article.
Cation involvement in telomestatin binding to g-quadruplex DNA.
Rosu F, Gabelica V, Smargiasso N, Mazzucchelli G, Shin-Ya K, De Pauw E. Rosu F, et al. Among authors: mazzucchelli g. J Nucleic Acids. 2010;2010:121259. doi: 10.4061/2010/121259. Epub 2010 Jun 16. J Nucleic Acids. 2010. PMID: 20700418 Free PMC article.
89 results