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Structural basis for regulation of the human acetyl-CoA thioesterase 12 and interactions with the steroidogenic acute regulatory protein-related lipid transfer (START) domain.
Swarbrick CM, Roman N, Cowieson N, Patterson EI, Nanson J, Siponen MI, Berglund H, Lehtiö L, Forwood JK. Swarbrick CM, et al. Among authors: cowieson n. J Biol Chem. 2014 Aug 29;289(35):24263-74. doi: 10.1074/jbc.M114.589408. Epub 2014 Jul 7. J Biol Chem. 2014. PMID: 25002576 Free PMC article.
A medium or high throughput protein refolding assay.
Cowieson NP, Wensley B, Robin G, Guncar G, Forwood J, Hume DA, Kobe B, Martin JL. Cowieson NP, et al. Methods Mol Biol. 2008;426:269-75. doi: 10.1007/978-1-60327-058-8_17. Methods Mol Biol. 2008. PMID: 18542870
Dimerization of plant defensin NaD1 enhances its antifungal activity.
Lay FT, Mills GD, Poon IK, Cowieson NP, Kirby N, Baxter AA, van der Weerden NL, Dogovski C, Perugini MA, Anderson MA, Kvansakul M, Hulett MD. Lay FT, et al. Among authors: cowieson np. J Biol Chem. 2012 Jun 8;287(24):19961-72. doi: 10.1074/jbc.M111.331009. Epub 2012 Apr 17. J Biol Chem. 2012. PMID: 22511788 Free PMC article.
Structural and Functional Characterization of the PaaI Thioesterase from Streptococcus pneumoniae Reveals a Dual Specificity for Phenylacetyl-CoA and Medium-chain Fatty Acyl-CoAs and a Novel CoA-induced Fit Mechanism.
Khandokar YB, Srivastava P, Sarker S, Swarbrick CMD, Aragao D, Cowieson N, Forwood JK. Khandokar YB, et al. Among authors: cowieson n. J Biol Chem. 2016 Jan 22;291(4):1866-1876. doi: 10.1074/jbc.M115.677484. Epub 2015 Nov 4. J Biol Chem. 2016. PMID: 26538563 Free PMC article.
66 results