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A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity.
Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE, Kiritsy CP, Healey SE, DiMare M, Sanford DG, Munford RS, Bachovchin WW, Golub TR. Bachovchin DA, et al. Among authors: kiritsy cp. Nat Chem Biol. 2014 Aug;10(8):656-63. doi: 10.1038/nchembio.1578. Epub 2014 Jul 6. Nat Chem Biol. 2014. PMID: 24997602 Free PMC article.
A pan inhibitor of DASH family enzymes induces immunogenic modulation and sensitizes murine and human carcinoma cells to antigen-specific cytotoxic T lymphocyte killing: implications for combination therapy with cancer vaccines.
Donahue RN, Duncan BB, Fry TJ, Jones B, Bachovchin WW, Kiritsy CP, Lai JH, Wu W, Zhao P, Liu Y, Tsang KY, Hodge JW. Donahue RN, et al. Among authors: kiritsy cp. Vaccine. 2014 May 30;32(26):3223-31. doi: 10.1016/j.vaccine.2014.04.008. Epub 2014 Apr 13. Vaccine. 2014. PMID: 24731809 Free PMC article.
11 results