Brodsky IE - Search Results

1

IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM.

Chung LK, Philip NH, Schmidt VA, Koller A, Strowig T, Flavell RA, Brodsky IE, Bliska JB. Chung LK, et al. Among authors: brodsky ie. mBio. 2014 Jul 1;5(4):e01402-14. doi: 10.1128/mBio.01402-14. mBio. 2014. PMID: 24987096 Free PMC article.

2

Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence.

Brodsky IE, Medzhitov R. Brodsky IE, et al. PLoS Pathog. 2008 May 16;4(5):e1000067. doi: 10.1371/journal.ppat.1000067. PLoS Pathog. 2008. PMID: 18483548 Free PMC article.

3

A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system.

Brodsky IE, Palm NW, Sadanand S, Ryndak MB, Sutterwala FS, Flavell RA, Bliska JB, Medzhitov R. Brodsky IE, et al. Cell Host Microbe. 2010 May 20;7(5):376-87. doi: 10.1016/j.chom.2010.04.009. Cell Host Microbe. 2010. PMID: 20478539 Free PMC article.

4

Pyroptosis: macrophage suicide exposes hidden invaders.

Brodsky IE, Medzhitov R. Brodsky IE, et al. Curr Biol. 2011 Jan 25;21(2):R72-5. doi: 10.1016/j.cub.2010.12.008. Curr Biol. 2011. PMID: 21256438 Free article.

5

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB. Zheng Y, et al. Among authors: brodsky ie. PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026. Epub 2011 Apr 21. PLoS Pathog. 2011. PMID: 21533069 Free PMC article.

6

Cell death programs in Yersinia immunity and pathogenesis.

Philip NH, Brodsky IE. Philip NH, et al. Among authors: brodsky ie. Front Cell Infect Microbiol. 2012 Nov 30;2:149. doi: 10.3389/fcimb.2012.00149. eCollection 2012. Front Cell Infect Microbiol. 2012. PMID: 23226685 Free PMC article. Review.

7

Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.

Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S. Casson CN, et al. Among authors: brodsky ie. PLoS Pathog. 2013;9(6):e1003400. doi: 10.1371/journal.ppat.1003400. Epub 2013 Jun 6. PLoS Pathog. 2013. PMID: 23762026 Free PMC article.

8

Modulation of innate immune responses by Yersinia type III secretion system translocators and effectors.

Bliska JB, Wang X, Viboud GI, Brodsky IE. Bliska JB, et al. Among authors: brodsky ie. Cell Microbiol. 2013 Oct;15(10):1622-31. doi: 10.1111/cmi.12164. Epub 2013 Jul 29. Cell Microbiol. 2013. PMID: 23834311 Free PMC article. Review.

9

Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome.

Wynosky-Dolfi MA, Snyder AG, Philip NH, Doonan PJ, Poffenberger MC, Avizonis D, Zwack EE, Riblett AM, Hu B, Strowig T, Flavell RA, Jones RG, Freedman BD, Brodsky IE. Wynosky-Dolfi MA, et al. Among authors: brodsky ie. J Exp Med. 2014 Apr 7;211(4):653-68. doi: 10.1084/jem.20130627. Epub 2014 Mar 17. J Exp Med. 2014. PMID: 24638169 Free PMC article.

10

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling.

Philip NH, Dillon CP, Snyder AG, Fitzgerald P, Wynosky-Dolfi MA, Zwack EE, Hu B, Fitzgerald L, Mauldin EA, Copenhaver AM, Shin S, Wei L, Parker M, Zhang J, Oberst A, Green DR, Brodsky IE. Philip NH, et al. Among authors: brodsky ie. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7385-90. doi: 10.1073/pnas.1403252111. Epub 2014 May 5. Proc Natl Acad Sci U S A. 2014. PMID: 24799700 Free PMC article.

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