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HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells.
Araya N, Sato T, Ando H, Tomaru U, Yoshida M, Coler-Reilly A, Yagishita N, Yamauchi J, Hasegawa A, Kannagi M, Hasegawa Y, Takahashi K, Kunitomo Y, Tanaka Y, Nakajima T, Nishioka K, Utsunomiya A, Jacobson S, Yamano Y. Araya N, et al. J Clin Invest. 2014 Aug;124(8):3431-42. doi: 10.1172/JCI75250. Epub 2014 Jun 24. J Clin Invest. 2014. PMID: 24960164 Free PMC article.
Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy.
Sato T, Coler-Reilly ALG, Yagishita N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y, Yamano Y. Sato T, et al. N Engl J Med. 2018 Feb 8;378(6):529-538. doi: 10.1056/NEJMoa1704827. N Engl J Med. 2018. PMID: 29414279 Free article. Clinical Trial.
Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy.
Yamauchi J, Coler-Reilly A, Sato T, Araya N, Yagishita N, Ando H, Kunitomo Y, Takahashi K, Tanaka Y, Shibagaki Y, Nishioka K, Nakajima T, Hasegawa Y, Utsunomiya A, Kimura K, Yamano Y. Yamauchi J, et al. J Infect Dis. 2015 Jan 15;211(2):238-48. doi: 10.1093/infdis/jiu438. Epub 2014 Aug 7. J Infect Dis. 2015. PMID: 25104771
Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis.
Nagasaka M, Yamagishi M, Yagishita N, Araya N, Kobayashi S, Makiyama J, Kubokawa M, Yamauchi J, Hasegawa D, Coler-Reilly ALG, Tsutsumi S, Uemura Y, Arai A, Takata A, Inoue E, Hasegawa Y, Watanabe T, Suzuki Y, Uchimaru K, Sato T, Yamano Y. Nagasaka M, et al. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11685-11691. doi: 10.1073/pnas.1920346117. Epub 2020 May 11. Proc Natl Acad Sci U S A. 2020. PMID: 32393644 Free PMC article.
Creation and validation of a bladder dysfunction symptom score for HTLV-1-associated myelopathy/tropical spastic paraparesis.
Yamakawa N, Yagishita N, Matsuo T, Yamauchi J, Ueno T, Inoue E, Takata A, Nagasaka M, Araya N, Hasegawa D, Coler-Reilly A, Tsutsumi S, Sato T, Araujo A, Casseb J, Gotuzzo E, Jacobson S, Martin F, Puccioni-Sohler M, Taylor GP, Yamano Y; Japan Clinical Research Group on HAM/TSP. Yamakawa N, et al. Orphanet J Rare Dis. 2020 Jul 3;15(1):175. doi: 10.1186/s13023-020-01451-3. Orphanet J Rare Dis. 2020. PMID: 32620176 Free PMC article.
31 results