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Phase 1 trial design: is 3 + 3 the best?
Hansen AR, Graham DM, Pond GR, Siu LL. Hansen AR, et al. Cancer Control. 2014 Jul;21(3):200-8. doi: 10.1177/107327481402100304. Cancer Control. 2014. PMID: 24955703 Free article. Review.
Tumour heterogeneity in the clinic.
Bedard PL, Hansen AR, Ratain MJ, Siu LL. Bedard PL, et al. Among authors: hansen ar. Nature. 2013 Sep 19;501(7467):355-64. doi: 10.1038/nature12627. Nature. 2013. PMID: 24048068 Free PMC article.
Early phase clinical trials to identify optimal dosing and safety.
Cook N, Hansen AR, Siu LL, Abdul Razak AR. Cook N, et al. Among authors: hansen ar. Mol Oncol. 2015 May;9(5):997-1007. doi: 10.1016/j.molonc.2014.07.025. Epub 2014 Aug 14. Mol Oncol. 2015. PMID: 25160636 Free PMC article. Review.
Refining American Joint Committee on Cancer/Union for International Cancer Control TNM stage and prognostic groups for human papillomavirus-related oropharyngeal carcinomas.
Huang SH, Xu W, Waldron J, Siu L, Shen X, Tong L, Ringash J, Bayley A, Kim J, Hope A, Cho J, Giuliani M, Hansen A, Irish J, Gilbert R, Gullane P, Perez-Ordonez B, Weinreb I, Liu FF, O'Sullivan B. Huang SH, et al. J Clin Oncol. 2015 Mar 10;33(8):836-45. doi: 10.1200/JCO.2014.58.6412. Epub 2015 Feb 9. J Clin Oncol. 2015. PMID: 25667292
Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors.
Meulendijks D, Lassen UN, Siu LL, Huitema AD, Karanikas V, Mau-Sorensen M, Jonker DJ, Hansen AR, Simcox ME, Schostack KJ, Bottino D, Zhong H, Roessler M, Vega-Harring SM, Jarutat T, Geho D, Wang K, DeMario M, Goss GD, Schellens JH. Meulendijks D, et al. Among authors: hansen ar. Clin Cancer Res. 2016 Feb 15;22(4):858-67. doi: 10.1158/1078-0432.CCR-15-1506. Epub 2015 Oct 7. Clin Cancer Res. 2016. PMID: 26446946 Clinical Trial.
272 results