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Research capacity. Enabling the genomic revolution in Africa.
H3Africa Consortium; Rotimi C, Abayomi A, Abimiku A, Adabayeri VM, Adebamowo C, Adebiyi E, Ademola AD, Adeyemo A, Adu D, Affolabi D, Agongo G, Ajayi S, Akarolo-Anthony S, Akinyemi R, Akpalu A, Alberts M, Alonso Betancourt O, Alzohairy AM, Ameni G, Amodu O, Anabwani G, Andersen K, Arogundade F, Arulogun O, Asogun D, Bakare R, Balde N, Baniecki ML, Beiswanger C, Benkahla A, Bethke L, Boehnke M, Boima V, Brandful J, Brooks AI, Brosius FC, Brown C, Bucheton B, Burke DT, Burnett BG, Carrington-Lawrence S, Carstens N, Chisi J, Christoffels A, Cooper R, Cordell H, Crowther N, Croxton T, de Vries J, Derr L, Donkor P, Doumbia S, Duncanson A, Ekem I, El Sayed A, Engel ME, Enyaru JC, Everett D, Fadlelmola FM, Fakunle E, Fischbeck KH, Fischer A, Folarin O, Gamieldien J, Garry RF, Gaseitsiwe S, Gbadegesin R, Ghansah A, Giovanni M, Goesbeck P, Gomez-Olive FX, Grant DS, Grewal R, Guyer M, Hanchard NA, Happi CT, Hazelhurst S, Hennig BJ, Hertz- C, Fowler, Hide W, Hilderbrandt F, Hugo-Hamman C, Ibrahim ME, James R, Jaufeerally-Fakim Y, Jenkins C, Jentsch U, Jiang PP, Joloba M, Jongeneel V, Joubert F, Kader M, Kahn K, Kaleebu P, Kapiga SH, Kassim SK, Kasvosve I, Kayondo J, Keavney B, Kekitiinwa A, K… See abstract for full author list ➔ H3Africa Consortium, et al. Among authors: simuunza m. Science. 2014 Jun 20;344(6190):1346-8. doi: 10.1126/science.1251546. Science. 2014. PMID: 24948725 Free PMC article. No abstract available.
Copy number variation in human genomes from three major ethno-linguistic groups in Africa.
Nyangiri OA, Noyes H, Mulindwa J, Ilboudo H, Kabore JW, Ahouty B, Koffi M, Asina OF, Mumba D, Ofon E, Simo G, Kimuda MP, Enyaru J, Alibu VP, Kamoto K, Chisi J, Simuunza M, Camara M, Sidibe I, MacLeod A, Bucheton B, Hall N, Hertz-Fowler C, Matovu E; TrypanoGEN Research Group, as members of The H3Africa Consortium. Nyangiri OA, et al. Among authors: simuunza m. BMC Genomics. 2020 Apr 10;21(1):289. doi: 10.1186/s12864-020-6669-y. BMC Genomics. 2020. PMID: 32272904 Free PMC article.
High-depth African genomes inform human migration and health.
Choudhury A, Aron S, Botigué LR, Sengupta D, Botha G, Bensellak T, Wells G, Kumuthini J, Shriner D, Fakim YJ, Ghoorah AW, Dareng E, Odia T, Falola O, Adebiyi E, Hazelhurst S, Mazandu G, Nyangiri OA, Mbiyavanga M, Benkahla A, Kassim SK, Mulder N, Adebamowo SN, Chimusa ER, Muzny D, Metcalf G, Gibbs RA; TrypanoGEN Research Group; Rotimi C, Ramsay M; H3Africa Consortium; Adeyemo AA, Lombard Z, Hanchard NA. Choudhury A, et al. Nature. 2020 Oct;586(7831):741-748. doi: 10.1038/s41586-020-2859-7. Epub 2020 Oct 28. Nature. 2020. PMID: 33116287 Free PMC article.
Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis.
Ilboudo H, Noyes H, Mulindwa J, Kimuda MP, Koffi M, Kaboré JW, Ahouty B, Ngoyi DM, Fataki O, Simo G, Ofon E, Enyaru J, Chisi J, Kamoto K, Simuunza M, Alibu VP, Lejon V, Jamonneau V, Macleod A, Camara M, Bucheton B, Hertz-Fowler C, Sidibe I, Matovu E; TrypanoGEN Research Group as members of The H3Africa Consortium. Ilboudo H, et al. Among authors: simuunza m. PLoS Negl Trop Dis. 2017 Jun 1;11(6):e0005438. doi: 10.1371/journal.pntd.0005438. eCollection 2017 Jun. PLoS Negl Trop Dis. 2017. PMID: 28570558 Free PMC article. No abstract available.
Characterization of CYP2D6 Pharmacogenetic Variation in Sub-Saharan African Populations.
Twesigomwe D, Drögemöller BI, Wright GEB, Adebamowo C, Agongo G, Boua PR, Matshaba M, Paximadis M, Ramsay M, Simo G, Simuunza MC, Tiemessen CT, Lombard Z, Hazelhurst S. Twesigomwe D, et al. Among authors: simuunza mc. Clin Pharmacol Ther. 2023 Mar;113(3):643-659. doi: 10.1002/cpt.2749. Epub 2022 Oct 21. Clin Pharmacol Ther. 2023. PMID: 36111505 Free PMC article.
A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations.
Ofon E, Noyes H, Mulindwa J, Ilboudo H, Simuunza M, Ebo'o V, Njiokou F, Koffi M, Bucheton B, Fogue P, Hertz-Fowler C, MacLeod A, Simo G; TrypanoGEN Research Group, as members of The H3Africa Consortium. Ofon E, et al. Among authors: simuunza m. PLoS Negl Trop Dis. 2017 Oct 27;11(10):e0005979. doi: 10.1371/journal.pntd.0005979. eCollection 2017 Oct. PLoS Negl Trop Dis. 2017. PMID: 29077717 Free PMC article.
Author Correction: High-depth African genomes inform human migration and health.
Choudhury A, Aron S, Botigué LR, Sengupta D, Botha G, Bensellak T, Wells G, Kumuthini J, Shriner D, Fakim YJ, Ghoorah AW, Dareng E, Odia T, Falola O, Adebiyi E, Hazelhurst S, Mazandu G, Nyangiri OA, Mbiyavanga M, Benkahla A, Kassim SK, Mulder N, Adebamowo SN, Chimusa ER, Muzny D, Metcalf G, Gibbs RA; TrypanoGEN Research Group; Rotimi C, Ramsay M; H3Africa Consortium; Adeyemo AA, Lombard Z, Hanchard NA. Choudhury A, et al. Nature. 2021 Apr;592(7856):E26. doi: 10.1038/s41586-021-03286-9. Nature. 2021. PMID: 33846614 Free PMC article. No abstract available.
The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations.
da Rocha JEB, Othman H, Botha G, Cottino L, Twesigomwe D, Ahmed S, Drögemöller BI, Fadlelmola FM, Machanick P, Mbiyavanga M, Panji S, Wright GEB, Adebamowo C, Matshaba M, Ramsay M, Simo G, Simuunza MC, Tiemessen CT, Baldwin S, Chiano M, Cox C, Gross AS, Thomas P, Gamo FJ, Hazelhurst S. da Rocha JEB, et al. Among authors: simuunza mc. Front Pharmacol. 2021 Apr 28;12:634016. doi: 10.3389/fphar.2021.634016. eCollection 2021. Front Pharmacol. 2021. PMID: 34721006 Free PMC article.
High Levels of Genetic Diversity within Nilo-Saharan Populations: Implications for Human Adaptation.
Mulindwa J, Noyes H, Ilboudo H, Pagani L, Nyangiri O, Kimuda MP, Ahouty B, Asina OF, Ofon E, Kamoto K, Kabore JW, Koffi M, Ngoyi DM, Simo G, Chisi J, Sidibe I, Enyaru J, Simuunza M, Alibu P, Jamonneau V, Camara M, Tait A, Hall N, Bucheton B, MacLeod A, Hertz-Fowler C, Matovu E; TrypanoGEN Research Group of the H3Africa Consortium. Mulindwa J, et al. Among authors: simuunza m. Am J Hum Genet. 2020 Sep 3;107(3):473-486. doi: 10.1016/j.ajhg.2020.07.007. Epub 2020 Aug 10. Am J Hum Genet. 2020. PMID: 32781046 Free PMC article.
Exploring the effect of human and animal population growth on vector-borne disease transmission with an agent-based model of Rhodesian human African trypanosomiasis in eastern province, Zambia.
Alderton S, Macleod ET, Anderson NE, Machila N, Simuunza M, Welburn SC, Atkinson PM. Alderton S, et al. Among authors: simuunza m. PLoS Negl Trop Dis. 2018 Nov 8;12(11):e0006905. doi: 10.1371/journal.pntd.0006905. eCollection 2018 Nov. PLoS Negl Trop Dis. 2018. PMID: 30408045 Free PMC article.
79 results