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LASSBio-881: an N-acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by capsaicin or partial sciatic ligation.
Tributino JL, Santos ML, Mesquita CM, Lima CK, Silva LL, Maia RC, Duarte CD, Barreiro EJ, Fraga CA, Castro NG, Miranda AL, Guimaraes MZ. Tributino JL, et al. Among authors: guimaraes mz. Br J Pharmacol. 2010 Apr;159(8):1716-23. doi: 10.1111/j.1476-5381.2010.00672.x. Br J Pharmacol. 2010. PMID: 20401963 Free PMC article.
Cannabinoids modulate cell survival in embryoid bodies.
Nones J, Spohr TC, Furtado DR, Sartore RC, Paulsen BS, Guimarães MZ, Rehen SK. Nones J, et al. Among authors: guimaraes mz. Cell Biol Int. 2010 Mar 12;34(4):399-408. doi: 10.1042/CBI20090036. Cell Biol Int. 2010. PMID: 19947926
Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor.
Pamplona FA, Ferreira J, Menezes de Lima O Jr, Duarte FS, Bento AF, Forner S, Villarinho JG, Bellocchio L, Wotjak CT, Lerner R, Monory K, Lutz B, Canetti C, Matias I, Calixto JB, Marsicano G, Guimarães MZ, Takahashi RN. Pamplona FA, et al. Among authors: guimaraes mz. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21134-9. doi: 10.1073/pnas.1202906109. Epub 2012 Nov 12. Proc Natl Acad Sci U S A. 2012. PMID: 23150578 Free PMC article.
Oligomeric α-Synuclein induces skin degeneration in reconstructed human epidermis.
Oliveira JT, Dakic V, Vitória G, Pedrosa CDSG, Mendes M, Aragão LGHS, Cardim-Pires TR, Lelièvre D, Furtado DR, Pinheiro RO, Foguel D, Breton L, Bouez C, De Vecchi R, Guimarães MZP, Rehen S. Oliveira JT, et al. Among authors: guimaraes mzp. Neurobiol Aging. 2022 May;113:108-117. doi: 10.1016/j.neurobiolaging.2022.02.010. Epub 2022 Feb 26. Neurobiol Aging. 2022. PMID: 35325812 Free article.
WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2.
Aragão LGHS, Oliveira JT, Temerozo JR, Mendes MA, Salerno JA, Pedrosa CSG, Puig-Pijuan T, Veríssimo CP, Ornelas IM, Torquato T, Vitória G, Sacramento CQ, Fintelman-Rodrigues N, da Silva Gomes Dias S, Cardoso Soares V, Souza LRQ, Karmirian K, Goto-Silva L, Biagi D, Cruvinel EM, Dariolli R, Furtado DR, Bozza PT, Borges HL, Souza TML, Guimarães MZP, Rehen SK. Aragão LGHS, et al. Among authors: guimaraes mzp. PeerJ. 2021 Oct 8;9:e12262. doi: 10.7717/peerj.12262. eCollection 2021. PeerJ. 2021. PMID: 34707939 Free PMC article.
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