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Malaria drives T cells to exhaustion.
Front Microbiol. 2014 May 27;5:249. doi: 10.3389/fmicb.2014.00249. eCollection 2014.
Front Microbiol. 2014.
PMID: 24904561
Free PMC article.
Review.
PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.
Horne-Debets JM, Faleiro R, Karunarathne DS, Liu XQ, Lineburg KE, Poh CM, Grotenbreg GM, Hill GR, MacDonald KP, Good MF, Renia L, Ahmed R, Sharpe AH, Wykes MN.
Horne-Debets JM, et al. Among authors: karunarathne ds.
Cell Rep. 2013 Dec 12;5(5):1204-13. doi: 10.1016/j.celrep.2013.11.002. Epub 2013 Dec 5.
Cell Rep. 2013.
PMID: 24316071
Free article.
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The Contribution of Co-signaling Pathways to Anti-malarial T Cell Immunity.
Faleiro R, Karunarathne DS, Horne-Debets JM, Wykes M.
Faleiro R, et al. Among authors: karunarathne ds.
Front Immunol. 2018 Dec 14;9:2926. doi: 10.3389/fimmu.2018.02926. eCollection 2018.
Front Immunol. 2018.
PMID: 30631323
Free PMC article.
Review.
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Mice lacking Programmed cell death-1 show a role for CD8(+) T cells in long-term immunity against blood-stage malaria.
Horne-Debets JM, Karunarathne DS, Faleiro RJ, Poh CM, Renia L, Wykes MN.
Horne-Debets JM, et al. Among authors: karunarathne ds.
Sci Rep. 2016 May 24;6:26210. doi: 10.1038/srep26210.
Sci Rep. 2016.
PMID: 27217330
Free PMC article.
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Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity.
Karunarathne DS, Horne-Debets JM, Huang JX, Faleiro R, Leow CY, Amante F, Watkins TS, Miles JJ, Dwyer PJ, Stacey KJ, Yarski M, Poh CM, Lee JS, Cooper MA, Rénia L, Richard D, McCarthy JS, Sharpe AH, Wykes MN.
Karunarathne DS, et al.
Immunity. 2016 Aug 16;45(2):333-45. doi: 10.1016/j.immuni.2016.07.017.
Immunity. 2016.
PMID: 27533014
Free article.
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A Peptide-Based PD1 Antagonist Enhances T-Cell Priming and Efficacy of a Prophylactic Malaria Vaccine and Promotes Survival in a Lethal Malaria Model.
Phares TW, Kotraiah V, Karunarathne DS, Huang J, Browne CD, Buontempo P, Mansour M, Noe AR, Wykes MN, Pannucci J, Tsuji M, Gutierrez GM.
Phares TW, et al. Among authors: karunarathne ds.
Front Immunol. 2020 Jul 9;11:1377. doi: 10.3389/fimmu.2020.01377. eCollection 2020.
Front Immunol. 2020.
PMID: 32733457
Free PMC article.
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Crohn's disease is facilitated by a disturbance of programmed death-1 ligand 2 on blood dendritic cells.
Faleiro R, Liu J, Karunarathne D, Edmundson A, Winterford C, Nguyen TH, Simms LA, Radford-Smith G, Wykes M.
Faleiro R, et al.
Clin Transl Immunology. 2019 Jul 25;8(7):e01071. doi: 10.1002/cti2.1071. eCollection 2019.
Clin Transl Immunology. 2019.
PMID: 31367378
Free PMC article.
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BRN2 expression increases anoikis resistance in melanoma.
Pierce CJ, Simmons JL, Broit N, Karunarathne D, Ng MF, Boyle GM.
Pierce CJ, et al.
Oncogenesis. 2020 Jul 6;9(7):64. doi: 10.1038/s41389-020-00247-1.
Oncogenesis. 2020.
PMID: 32632141
Free PMC article.
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