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Malaria drives T cells to exhaustion.
Wykes MN, Horne-Debets JM, Leow CY, Karunarathne DS. Wykes MN, et al. Among authors: horne debets jm. Front Microbiol. 2014 May 27;5:249. doi: 10.3389/fmicb.2014.00249. eCollection 2014. Front Microbiol. 2014. PMID: 24904561 Free PMC article. Review.
PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.
Horne-Debets JM, Faleiro R, Karunarathne DS, Liu XQ, Lineburg KE, Poh CM, Grotenbreg GM, Hill GR, MacDonald KP, Good MF, Renia L, Ahmed R, Sharpe AH, Wykes MN. Horne-Debets JM, et al. Cell Rep. 2013 Dec 12;5(5):1204-13. doi: 10.1016/j.celrep.2013.11.002. Epub 2013 Dec 5. Cell Rep. 2013. PMID: 24316071 Free article.
Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity.
Karunarathne DS, Horne-Debets JM, Huang JX, Faleiro R, Leow CY, Amante F, Watkins TS, Miles JJ, Dwyer PJ, Stacey KJ, Yarski M, Poh CM, Lee JS, Cooper MA, Rénia L, Richard D, McCarthy JS, Sharpe AH, Wykes MN. Karunarathne DS, et al. Among authors: horne debets jm. Immunity. 2016 Aug 16;45(2):333-45. doi: 10.1016/j.immuni.2016.07.017. Immunity. 2016. PMID: 27533014 Free article.
Dendritic cells: the Trojan horse of malaria?
Wykes MN, Horne-Debets J. Wykes MN, et al. Int J Parasitol. 2012 May 15;42(6):583-7. doi: 10.1016/j.ijpara.2012.03.002. Epub 2012 Mar 21. Int J Parasitol. 2012. PMID: 22726753