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Inhibition of cell proliferation, cytotoxicity and induction of apoptosis of 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene in gastrointestinal tumour cell lines and preliminary evaluation of its toxicity in vivo.
Dell'Erba C, Chiavarina B, Fenoglio C, Petrillo G, Cordazzo C, Boncompagni E, Spinelli D, Ognio E, Aiello C, Mariggiò MA, Viale M. Dell'Erba C, et al. Among authors: spinelli d. Pharmacol Res. 2005 Sep;52(3):271-82. doi: 10.1016/j.phrs.2005.03.011. Pharmacol Res. 2005. PMID: 15921920
Calcium channel antagonists discovered by a multidisciplinary approach.
Carosati E, Cruciani G, Chiarini A, Budriesi R, Ioan P, Spisani R, Spinelli D, Cosimelli B, Fusi F, Frosini M, Matucci R, Gasparrini F, Ciogli A, Stephens PJ, Devlin FJ. Carosati E, et al. Among authors: spinelli d. J Med Chem. 2006 Aug 24;49(17):5206-16. doi: 10.1021/jm0604373. J Med Chem. 2006. PMID: 16913709
Determination of the absolute configuration of a chiral oxadiazol-3-one calcium channel blocker, resolved using chiral chromatography, via concerted density functional theory calculations of its vibrational circular dichroism, electronic circular dichroism, and optical rotation.
Stephens PJ, Devlin FJ, Gasparrini F, Ciogli A, Spinelli D, Cosimelli B. Stephens PJ, et al. Among authors: spinelli d. J Org Chem. 2007 Jun 22;72(13):4707-15. doi: 10.1021/jo070302k. Epub 2007 May 22. J Org Chem. 2007. PMID: 17516678
360 results