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Page 1
Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.
ACS Med Chem Lett. 2010 Jan 19;1(1):30-4. doi: 10.1021/ml900018m. eCollection 2010 Apr 8.
ACS Med Chem Lett. 2010.
PMID: 24900171
Free PMC article.
Antitumor activity of an allosteric inhibitor of centromere-associated protein-E.
Wood KW, Lad L, Luo L, Qian X, Knight SD, Nevins N, Brejc K, Sutton D, Gilmartin AG, Chua PR, Desai R, Schauer SP, McNulty DE, Annan RS, Belmont LD, Garcia C, Lee Y, Diamond MA, Faucette LF, Giardiniere M, Zhang S, Sun CM, Vidal JD, Lichtsteiner S, Cornwell WD, Greshock JD, Wooster RF, Finer JT, Copeland RA, Huang PS, Morgans DJ Jr, Dhanak D, Bergnes G, Sakowicz R, Jackson JR.
Wood KW, et al. Among authors: bergnes g.
Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5839-44. doi: 10.1073/pnas.0915068107. Epub 2010 Feb 18.
Proc Natl Acad Sci U S A. 2010.
PMID: 20167803
Free PMC article.
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Mitotic kinesins: prospects for antimitotic drug discovery.
Bergnes G, Brejc K, Belmont L.
Bergnes G, et al.
Curr Top Med Chem. 2005;5(2):127-45. doi: 10.2174/1568026053507697.
Curr Top Med Chem. 2005.
PMID: 15853642
Review.
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Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.
Collibee SE, Bergnes G, Muci A, Browne WF 4th, Garard M, Hinken AC, Russell AJ, Suehiro I, Hartman J, Kawas R, Lu PP, Lee KH, Marquez D, Tomlinson M, Xu D, Kennedy A, Hwee D, Schaletzky J, Leung K, Malik FI, Morgans DJ Jr, Morgan BP.
Collibee SE, et al. Among authors: bergnes g.
ACS Med Chem Lett. 2018 Feb 13;9(4):354-358. doi: 10.1021/acsmedchemlett.7b00546. eCollection 2018 Apr 12.
ACS Med Chem Lett. 2018.
PMID: 29670700
Free PMC article.
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Discovery of Reldesemtiv, a Fast Skeletal Muscle Troponin Activator for the Treatment of Impaired Muscle Function.
Collibee SE, Bergnes G, Chuang C, Ashcraft L, Gardina J, Garard M, Jamison CR, Lu K, Lu PP, Muci A, Romero A, Valkevich E, Wang W, Warrington J, Yao B, Durham N, Hartman J, Marquez A, Hinken A, Schaletzky J, Xu D, Hwee DT, Morgans D, Malik FI, Morgan BP.
Collibee SE, et al. Among authors: bergnes g.
J Med Chem. 2021 Oct 28;64(20):14930-14941. doi: 10.1021/acs.jmedchem.1c01067. Epub 2021 Oct 12.
J Med Chem. 2021.
PMID: 34636234
Free article.
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Antifungal activity of a Candida albicans GGTase I inhibitor-alanine conjugate. Inhibition of Rho1p prenylation in C. albicans.
Murthi KK, Smith SE, Kluge AF, Bergnes G, Bureau P, Berlin V.
Murthi KK, et al. Among authors: bergnes g.
Bioorg Med Chem Lett. 2003 Jun 2;13(11):1935-7. doi: 10.1016/s0960-894x(03)00320-2.
Bioorg Med Chem Lett. 2003.
PMID: 12749902
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Generation of an Ugi library of phosphate mimic-containing compounds and identification of novel dual specific phosphatase inhibitors.
Bergnes G, Gilliam CL, Boisclair MD, Blanchard JL, Blake KV, Epstein DM, Pal K.
Bergnes G, et al.
Bioorg Med Chem Lett. 1999 Oct 4;9(19):2849-54. doi: 10.1016/s0960-894x(99)00497-7.
Bioorg Med Chem Lett. 1999.
PMID: 10522704
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Creatine and phosphocreatine analogs: anticancer activity and enzymatic analysis.
Bergnes G, Yuan W, Khandekar VS, O'Keefe MM, Martin KJ, Teicher BA, Kaddurah-Daouk R.
Bergnes G, et al.
Oncol Res. 1996;8(3):121-30.
Oncol Res. 1996.
PMID: 8823808
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