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Tumor necrosis factor-alpha activates signal transduction in hypothalamus and modulates the expression of pro-inflammatory proteins and orexigenic/anorexigenic neurotransmitters.
Amaral ME, Barbuio R, Milanski M, Romanatto T, Barbosa HC, Nadruz W, Bertolo MB, Boschero AC, Saad MJ, Franchini KG, Velloso LA. Amaral ME, et al. Among authors: velloso la. J Neurochem. 2006 Jul;98(1):203-12. doi: 10.1111/j.1471-4159.2006.03857.x. Epub 2006 Apr 21. J Neurochem. 2006. PMID: 16638016 Free article.
Ablation of primary afferent neurons by neonatal capsaicin treatment reduces the susceptibility of the portal hypertensive gastric mucosa to ethanol-induced injury in cirrhotic rats.
Camara PR, Ferraz GJ, Franco-Penteado CF, Sbragia-Neto L, Meirelles LR, Teixeira SA, Muscara MN, Velloso LA, Antunes E, Ferraz JG. Camara PR, et al. Among authors: velloso la. Eur J Pharmacol. 2008 Jul 28;589(1-3):245-50. doi: 10.1016/j.ejphar.2008.05.004. Epub 2008 May 16. Eur J Pharmacol. 2008. PMID: 18555214
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity.
Milanski M, Degasperi G, Coope A, Morari J, Denis R, Cintra DE, Tsukumo DM, Anhe G, Amaral ME, Takahashi HK, Curi R, Oliveira HC, Carvalheira JB, Bordin S, Saad MJ, Velloso LA. Milanski M, et al. Among authors: velloso la. J Neurosci. 2009 Jan 14;29(2):359-70. doi: 10.1523/JNEUROSCI.2760-08.2009. J Neurosci. 2009. PMID: 19144836 Free PMC article.
High-fat diet induces apoptosis of hypothalamic neurons.
Moraes JC, Coope A, Morari J, Cintra DE, Roman EA, Pauli JR, Romanatto T, Carvalheira JB, Oliveira AL, Saad MJ, Velloso LA. Moraes JC, et al. Among authors: velloso la. PLoS One. 2009;4(4):e5045. doi: 10.1371/journal.pone.0005045. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340313 Free PMC article.
Deletion of tumor necrosis factor-alpha receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis.
Romanatto T, Roman EA, Arruda AP, Denis RG, Solon C, Milanski M, Moraes JC, Bonfleur ML, Degasperi GR, Picardi PK, Hirabara S, Boschero AC, Curi R, Velloso LA. Romanatto T, et al. Among authors: velloso la. J Biol Chem. 2009 Dec 25;284(52):36213-36222. doi: 10.1074/jbc.M109.030874. Epub 2009 Oct 26. J Biol Chem. 2009. PMID: 19858212 Free PMC article. Retracted.
383 results