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ATM serine-1981 phosphorylation is a plausible biomarker.
Bakkenist CJ, Beumer JH, Schmitz JC. Bakkenist CJ, et al. Among authors: beumer jh. Cell Cycle. 2015;14(20):3207-8. doi: 10.1080/15384101.2015.1084205. Cell Cycle. 2015. PMID: 26517194 Free PMC article. No abstract available.
Therapeutic drug monitoring of 5-fluorouracil.
Lee JJ, Beumer JH, Chu E. Lee JJ, et al. Among authors: beumer jh. Cancer Chemother Pharmacol. 2016 Sep;78(3):447-64. doi: 10.1007/s00280-016-3054-2. Epub 2016 May 23. Cancer Chemother Pharmacol. 2016. PMID: 27217046 Free PMC article. Review.
Phase I study of veliparib in combination with gemcitabine.
Stoller R, Schmitz JC, Ding F, Puhalla S, Belani CP, Appleman L, Lin Y, Jiang Y, Almokadem S, Petro D, Holleran J, Kiesel BF, Ken Czambel R, Carneiro BA, Kontopodis E, Hershberger PA, Rachid M, Chen A, Chu E, Beumer JH. Stoller R, et al. Among authors: beumer jh. Cancer Chemother Pharmacol. 2017 Sep;80(3):631-643. doi: 10.1007/s00280-017-3409-3. Epub 2017 Aug 2. Cancer Chemother Pharmacol. 2017. PMID: 28770300 Free PMC article. Clinical Trial.
A phase i study of DMS612, a novel bifunctional alkylating agent.
Appleman LJ, Balasubramaniam S, Parise RA, Bryla C, Redon CE, Nakamura AJ, Bonner WM, Wright JJ, Piekarz R, Kohler DR, Jiang Y, Belani CP, Eiseman J, Chu E, Beumer JH, Bates SE. Appleman LJ, et al. Among authors: beumer jh. Clin Cancer Res. 2015 Feb 15;21(4):721-9. doi: 10.1158/1078-0432.CCR-14-1333. Epub 2014 Dec 2. Clin Cancer Res. 2015. PMID: 25467180 Free PMC article. Clinical Trial.
Therapeutic Drug Monitoring in Oncology: International Association of Therapeutic Drug Monitoring and Clinical Toxicology Recommendations for 5-Fluorouracil Therapy.
Beumer JH, Chu E, Allegra C, Tanigawara Y, Milano G, Diasio R, Kim TW, Mathijssen RH, Zhang L, Arnold D, Muneoka K, Boku N, Joerger M. Beumer JH, et al. Clin Pharmacol Ther. 2019 Mar;105(3):598-613. doi: 10.1002/cpt.1124. Epub 2018 Sep 11. Clin Pharmacol Ther. 2019. PMID: 29923599 Free PMC article. Review.
201 results