Noto PB - Search Results

1

The medicinal chemistry of liver X receptor (LXR) modulators.

Tice CM, Noto PB, Fan KY, Zhuang L, Lala DS, Singh SB. Tice CM, et al. Among authors: noto pb. J Med Chem. 2014 Sep 11;57(17):7182-205. doi: 10.1021/jm500442z. Epub 2014 May 28. J Med Chem. 2014. PMID: 24832115

2

Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists.

Lotesta SD, Marcus AP, Zheng Y, Leftheris K, Noto PB, Meng S, Kandpal G, Chen G, Zhou J, McKeever B, Bukhtiyarov Y, Zhao Y, Lala DS, Singh SB, McGeehan GM. Lotesta SD, et al. Among authors: noto pb. Bioorg Med Chem. 2016 Mar 15;24(6):1384-91. doi: 10.1016/j.bmc.2016.02.014. Epub 2016 Feb 9. Bioorg Med Chem. 2016. PMID: 26897089

3

Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist.

Zheng Y, Zhuang L, Fan KY, Tice CM, Zhao W, Dong C, Lotesta SD, Leftheris K, Lindblom PR, Liu Z, Shimada J, Noto PB, Meng S, Hardy A, Howard L, Krosky P, Guo J, Lipinski K, Kandpal G, Bukhtiyarov Y, Zhao Y, Lala D, Van Orden R, Zhou J, Chen G, Wu Z, McKeever BM, McGeehan GM, Gregg RE, Claremon DA, Singh SB. Zheng Y, et al. Among authors: noto pb. J Med Chem. 2016 Apr 14;59(7):3264-71. doi: 10.1021/acs.jmedchem.5b02029. Epub 2016 Mar 29. J Med Chem. 2016. PMID: 26990539

4

Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core.

Tice CM, Noto PB, Fan KY, Zhao W, Lotesta SD, Dong C, Marcus AP, Zheng YJ, Chen G, Wu Z, Van Orden R, Zhou J, Bukhtiyarov Y, Zhao Y, Lipinski K, Howard L, Guo J, Kandpal G, Meng S, Hardy A, Krosky P, Gregg RE, Leftheris K, McKeever BM, Singh SB, Lala D, McGeehan GM, Zhuang L, Claremon DA. Tice CM, et al. Among authors: noto pb. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5044-5050. doi: 10.1016/j.bmcl.2016.08.089. Epub 2016 Aug 29. Bioorg Med Chem Lett. 2016. PMID: 27599745

5

Regulation of sphingomyelin phosphodiesterase acid-like 3A gene (SMPDL3A) by liver X receptors.

Noto PB, Bukhtiyarov Y, Shi M, McKeever BM, McGeehan GM, Lala DS. Noto PB, et al. Mol Pharmacol. 2012 Oct;82(4):719-27. doi: 10.1124/mol.112.078865. Epub 2012 Jul 18. Mol Pharmacol. 2012. PMID: 22810003

6

Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues.

Noto PB, Sikorski TW, Zappacosta F, Wagner CD, Montes de Oca R, Szapacs ME, Annan RS, Liu Y, McHugh CF, Mohammad HP, Piccoli SP, Creasy CL. Noto PB, et al. Sci Rep. 2020 Dec 17;10(1):22155. doi: 10.1038/s41598-020-78800-6. Sci Rep. 2020. PMID: 33335114 Free PMC article.

7

Alternative stabilities of a proline-rich antibacterial peptide in vitro and in vivo.

Noto PB, Abbadessa G, Cassone M, Mateo GD, Agelan A, Wade JD, Szabo D, Kocsis B, Nagy K, Rozgonyi F, Otvos L Jr. Noto PB, et al. Protein Sci. 2008 Jul;17(7):1249-55. doi: 10.1110/ps.034330.108. Epub 2008 Apr 15. Protein Sci. 2008. PMID: 18413862 Free PMC article.

8

Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer.

Macaluso M, Montanari M, Noto PB, Gregorio V, Bronner C, Giordano A. Macaluso M, et al. Among authors: noto pb. Cancer Res. 2007 Aug 15;67(16):7731-7. doi: 10.1158/0008-5472.CAN-07-1476. Cancer Res. 2007. PMID: 17699777

9

Nuclear and cytoplasmic interaction of pRb2/p130 and ER-beta in MCF-7 breast cancer cells.

Macaluso M, Montanari M, Noto PB, Gregorio V, Surmacz E, Giordano A. Macaluso M, et al. Among authors: noto pb. Ann Oncol. 2006 Jun;17 Suppl 7:vii27-9. doi: 10.1093/annonc/mdl945. Ann Oncol. 2006. PMID: 16760287 Free article.

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