Ramos MT - Search Results

1

B-ring-aryl substituted luotonin A analogues with a new binding mode to the topoisomerase 1-DNA complex show enhanced cytotoxic activity.

González-Ruiz V, Pascua I, Fernández-Marcelo T, Ribelles P, Bianchini G, Sridharan V, Iniesta P, Ramos MT, Olives AI, Martín MA, Menéndez JC. González-Ruiz V, et al. Among authors: ramos mt. PLoS One. 2014 May 15;9(5):e95998. doi: 10.1371/journal.pone.0095998. eCollection 2014. PLoS One. 2014. PMID: 24830682 Free PMC article.

2

Synthesis of polysubstituted, functionalized quinolines through a metal-free domino process involving a C4–C3 functional group rearrangement.

Ribelles P, Ramos MT, Menéndez JC. Ribelles P, et al. Among authors: ramos mt. Org Lett. 2012 Mar 16;14(6):1402-4. doi: 10.1021/ol300132e. Epub 2012 Feb 8. Org Lett. 2012. PMID: 22316241

3

New types of reactivity of α,β-unsaturated N,N-dimethylhydrazones: chemodivergent diastereoselective synthesis of functionalized tetrahydroquinolines and hexahydropyrrolo[3,2-b]indoles.

Sridharan V, Ribelles P, Estévez V, Villacampa M, Ramos MT, Perumal PT, Menéndez JC. Sridharan V, et al. Among authors: ramos mt. Chemistry. 2012 Apr 16;18(16):5056-63. doi: 10.1002/chem.201103562. Epub 2012 Mar 5. Chemistry. 2012. PMID: 22392600

4

New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury.

Tenti G, Parada E, León R, Egea J, Martínez-Revelles S, Briones AM, Sridharan V, López MG, Ramos MT, Menéndez JC. Tenti G, et al. Among authors: ramos mt. J Med Chem. 2014 May 22;57(10):4313-23. doi: 10.1021/jm500263v. Epub 2014 May 7. J Med Chem. 2014. PMID: 24754640

5

Enantioselective catalytic Povarov reactions.

Clerigué J, Ramos MT, Menéndez JC. Clerigué J, et al. Among authors: ramos mt. Org Biomol Chem. 2022 Feb 23;20(8):1550-1581. doi: 10.1039/d1ob02270a. Org Biomol Chem. 2022. PMID: 34994760 Review.

6

Mechanochemical Aza-Vinylogous Povarov Reactions for the Synthesis of Highly Functionalized 1,2,3,4-Tetrahydroquinolines and 1,2,3,4-Tetrahydro-1,5-Naphthyridines.

Clerigué J, Ramos MT, Menéndez JC. Clerigué J, et al. Among authors: ramos mt. Molecules. 2021 Mar 2;26(5):1330. doi: 10.3390/molecules26051330. Molecules. 2021. PMID: 33801330 Free PMC article.

7

Synthesis of 1,4-Diazepanes and Benzo[b][1,4]diazepines by a Domino Process Involving the In Situ Generation of an Aza-Nazarov Reagent.

Maiti S, Leonardi M, Cores Á, Tenti G, Ramos MT, Villacampa M, Menéndez JC. Maiti S, et al. Among authors: ramos mt. J Org Chem. 2020 Sep 18;85(18):11924-11933. doi: 10.1021/acs.joc.0c01774. Epub 2020 Sep 3. J Org Chem. 2020. PMID: 32820631

8

Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer's Disease.

Michalska P, Mayo P, Fernández-Mendívil C, Tenti G, Duarte P, Buendia I, Ramos MT, López MG, Menéndez JC, León R. Michalska P, et al. Among authors: ramos mt. Antioxidants (Basel). 2020 Jul 22;9(8):650. doi: 10.3390/antiox9080650. Antioxidants (Basel). 2020. PMID: 32708053 Free PMC article.

9

ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia.

Buendia I, Tenti G, Michalska P, Méndez-López I, Luengo E, Satriani M, Padín-Nogueira F, López MG, Ramos MT, García AG, Menéndez JC, León R. Buendia I, et al. Among authors: ramos mt. ACS Chem Neurosci. 2017 Jan 18;8(1):67-81. doi: 10.1021/acschemneuro.6b00181. Epub 2016 Nov 22. ACS Chem Neurosci. 2017. PMID: 27731633

10

Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties.

Michalska P, Tenti G, Satriani M, Cores A, Ramos MT, García AG, Menéndez JC, León R. Michalska P, et al. Among authors: ramos mt. Drug Dev Res. 2020 May;81(3):283-294. doi: 10.1002/ddr.21618. Epub 2019 Nov 6. Drug Dev Res. 2020. PMID: 31693218

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