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New phosphodiesterase-4 inhibitors present airways relaxant activity in a guinea pig acute asthma model.
Naunyn Schmiedebergs Arch Pharmacol. 2024 Jun;397(6):4419-4434. doi: 10.1007/s00210-023-02905-8. Epub 2023 Dec 18.
Naunyn Schmiedebergs Arch Pharmacol. 2024.
PMID: 38108836
Synthesis and biological activity of novel 4-aminoquinoline/1,2,3-triazole hybrids against Leishmania amazonensis.
Glanzmann N, Antinarelli LMR, da Costa Nunes IK, Pereira HMG, Coelho EAF, Coimbra ES, da Silva AD.
Glanzmann N, et al. Among authors: da costa nunes ik.
Biomed Pharmacother. 2021 Sep;141:111857. doi: 10.1016/j.biopha.2021.111857. Epub 2021 Jul 13.
Biomed Pharmacother. 2021.
PMID: 34323702
Free article.
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Development of a liquid chromatography Q Exactive high resolution mass spectrometry method by the Box-Behnken design for the investigation of sibutramine urinary metabolites.
de Souza Anselmo C, Matias BF, Sardela VF, Ribeiro AF, da Costa Nunes IK, de Sousa VP, Pereira HMG.
de Souza Anselmo C, et al. Among authors: da costa nunes ik.
J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Sep 1;1125:121726. doi: 10.1016/j.jchromb.2019.121726. Epub 2019 Jul 20.
J Chromatogr B Analyt Technol Biomed Life Sci. 2019.
PMID: 31362180
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Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents.
Zapata-Sudo G, da Costa Nunes IK, Araujo JS, da Silva JS, Trachez MM, da Silva TF, da Costa FP, Sudo RT, Barreiro EJ, Lima LM.
Zapata-Sudo G, et al. Among authors: da costa nunes ik.
Drug Des Devel Ther. 2016 Sep 9;10:2869-2879. doi: 10.2147/DDDT.S108327. eCollection 2016.
Drug Des Devel Ther. 2016.
PMID: 27672310
Free PMC article.
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In vitro microsomal hepatic metabolism of antiasthmatic prototype LASSBio-448.
Costa Nunes IK, Tinoco LW, Martins-Junior H, Rezende C, Barreiro EJ, Lima LM.
Costa Nunes IK, et al.
Curr Top Med Chem. 2014;14(11):1388-98. doi: 10.2174/1568026614666140506123718.
Curr Top Med Chem. 2014.
PMID: 24805061
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