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Botch is a γ-glutamyl cyclotransferase that deglycinates and antagonizes Notch.
Chi Z, Byrne ST, Dolinko A, Harraz MM, Kim MS, Umanah G, Zhong J, Chen R, Zhang J, Xu J, Chen L, Pandey A, Dawson TM, Dawson VL. Chi Z, et al. Among authors: zhang j. Cell Rep. 2014 May 8;7(3):681-8. doi: 10.1016/j.celrep.2014.03.048. Epub 2014 Apr 24. Cell Rep. 2014. PMID: 24767995 Free PMC article.
Botch promotes neurogenesis by antagonizing Notch.
Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL. Chi Z, et al. Among authors: zhang j. Dev Cell. 2012 Apr 17;22(4):707-20. doi: 10.1016/j.devcel.2012.02.011. Epub 2012 Mar 22. Dev Cell. 2012. PMID: 22445366 Free PMC article.
AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF.
Umanah GKE, Ghasemi M, Yin X, Chang M, Kim JW, Zhang J, Ma E, Scarffe LA, Lee YI, Chen R, Tangella K, McNamara A, Abalde-Atristain L, Dar MA, Bennett S, Cortes M, Andrabi SA, Doulias PT, Ischiropoulos H, Dawson TM, Dawson VL. Umanah GKE, et al. Among authors: zhang j. Cell Rep. 2020 Nov 3;33(5):108329. doi: 10.1016/j.celrep.2020.108329. Cell Rep. 2020. PMID: 33147468 Free PMC article.
The AAA + ATPase Thorase is neuroprotective against ischemic injury.
Zhang J, Yang J, Wang H, Sherbini O, Keuss MJ, Umanah GK, Pai EL, Chi Z, Paldanius KM, He W, Wang H, Andrabi SA, Dawson TM, Dawson VL. Zhang J, et al. J Cereb Blood Flow Metab. 2019 Sep;39(9):1836-1848. doi: 10.1177/0271678X18769770. Epub 2018 Apr 16. J Cereb Blood Flow Metab. 2019. PMID: 29658368 Free PMC article.
Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.
Jiang H, Kang SU, Zhang S, Karuppagounder S, Xu J, Lee YK, Kang BG, Lee Y, Zhang J, Pletnikova O, Troncoso JC, Pirooznia S, Andrabi SA, Dawson VL, Dawson TM. Jiang H, et al. Among authors: zhang s, zhang j. eNeuro. 2016 Sep 2;3(4):ENEURO.0183-16.2016. doi: 10.1523/ENEURO.0183-16.2016. eCollection 2016 Jul-Aug. eNeuro. 2016. PMID: 27622213 Free PMC article.
Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3.
Mao X, Ou MT, Karuppagounder SS, Kam TI, Yin X, Xiong Y, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang J, Xu J, Chen R, Park H, Andrabi SA, Kang SU, Gonçalves RA, Liang Y, Zhang S, Qi C, Lam S, Keiler JA, Tyson J, Kim D, Panicker N, Yun SP, Workman CJ, Vignali DA, Dawson VL, Ko HS, Dawson TM. Mao X, et al. Among authors: zhang s, zhang j. Science. 2016 Sep 30;353(6307):aah3374. doi: 10.1126/science.aah3374. Science. 2016. PMID: 27708076 Free PMC article.
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