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An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. Seguin L, et al. Among authors: mielgo a. Nat Cell Biol. 2014 May;16(5):457-68. doi: 10.1038/ncb2953. Epub 2014 Apr 20. Nat Cell Biol. 2014. PMID: 24747441 Free PMC article.
Rab5 mediates caspase-8-promoted cell motility and metastasis.
Torres VA, Mielgo A, Barbero S, Hsiao R, Wilkins JA, Stupack DG. Torres VA, et al. Among authors: mielgo a. Mol Biol Cell. 2010 Jan 15;21(2):369-76. doi: 10.1091/mbc.e09-09-0769. Epub 2009 Nov 18. Mol Biol Cell. 2010. PMID: 19923319 Free PMC article.
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia.
Shields DJ, Niessen S, Murphy EA, Mielgo A, Desgrosellier JS, Lau SK, Barnes LA, Lesperance J, Bouvet M, Tarin D, Cravatt BF, Cheresh DA. Shields DJ, et al. Among authors: mielgo a. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2189-94. doi: 10.1073/pnas.0911646107. Epub 2009 Dec 28. Proc Natl Acad Sci U S A. 2010. PMID: 20080647 Free PMC article.
Oncogenic Ras/Src cooperativity in pancreatic neoplasia.
Shields DJ, Murphy EA, Desgrosellier JS, Mielgo A, Lau SK, Barnes LA, Lesperance J, Huang M, Schmedt C, Tarin D, Lowy AM, Cheresh DA. Shields DJ, et al. Among authors: mielgo a. Oncogene. 2011 May 5;30(18):2123-34. doi: 10.1038/onc.2010.589. Epub 2011 Jan 17. Oncogene. 2011. PMID: 21242978 Free PMC article.
A MEK-independent role for CRAF in mitosis and tumor progression.
Mielgo A, Seguin L, Huang M, Camargo MF, Anand S, Franovic A, Weis SM, Advani SJ, Murphy EA, Cheresh DA. Mielgo A, et al. Nat Med. 2011 Nov 13;17(12):1641-5. doi: 10.1038/nm.2464. Nat Med. 2011. PMID: 22081024 Free PMC article.
62 results