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An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. Seguin L, et al. Among authors: desgrosellier js. Nat Cell Biol. 2014 May;16(5):457-68. doi: 10.1038/ncb2953. Epub 2014 Apr 20. Nat Cell Biol. 2014. PMID: 24747441 Free PMC article.
Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers.
Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA. Seguin L, et al. Among authors: desgrosellier js. Cancer Discov. 2017 Dec;7(12):1464-1479. doi: 10.1158/2159-8290.CD-17-0539. Epub 2017 Sep 11. Cancer Discov. 2017. PMID: 28893801 Free PMC article.
Oncogenic Ras/Src cooperativity in pancreatic neoplasia.
Shields DJ, Murphy EA, Desgrosellier JS, Mielgo A, Lau SK, Barnes LA, Lesperance J, Huang M, Schmedt C, Tarin D, Lowy AM, Cheresh DA. Shields DJ, et al. Among authors: desgrosellier js. Oncogene. 2011 May 5;30(18):2123-34. doi: 10.1038/onc.2010.589. Epub 2011 Jan 17. Oncogene. 2011. PMID: 21242978 Free PMC article.
EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation.
Huang M, Anand S, Murphy EA, Desgrosellier JS, Stupack DG, Shattil SJ, Schlaepfer DD, Cheresh DA. Huang M, et al. Among authors: desgrosellier js. Oncogene. 2012 May 31;31(22):2783-93. doi: 10.1038/onc.2011.450. Epub 2011 Oct 3. Oncogene. 2012. PMID: 21963850 Free PMC article.
Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis.
Sun Q, Lesperance J, Wettersten H, Luterstein E, DeRose YS, Welm A, Cheresh DA, Desgrosellier JS. Sun Q, et al. Among authors: desgrosellier js. J Clin Invest. 2018 Jan 2;128(1):531-544. doi: 10.1172/JCI93707. Epub 2017 Dec 11. J Clin Invest. 2018. PMID: 29227280 Free PMC article.
23 results