Leung AW - Search Results

1

Harnessing the potential of lipid-based nanomedicines for type-specific ovarian cancer treatments.

Leung AW, Kalra J, Santos ND, Bally MB, Anglesio MS. Leung AW, et al. Nanomedicine (Lond). 2014 Mar;9(3):501-22. doi: 10.2217/nnm.13.220. Nanomedicine (Lond). 2014. PMID: 24746193 Review.

2

3'-Phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) knockdown sensitizes non-small cell lung cancer cells to DNA damaging agents.

Leung AW, Dragowska WH, Ricaurte D, Kwok B, Mathew V, Roosendaal J, Ahluwalia A, Warburton C, Laskin JJ, Stirling PC, Qadir MA, Bally MB. Leung AW, et al. Oncotarget. 2015 Jul 10;6(19):17161-77. doi: 10.18632/oncotarget.3635. Oncotarget. 2015. PMID: 26220590 Free PMC article.

3

Synthetic lethality in lung cancer and translation to clinical therapies.

Leung AW, de Silva T, Bally MB, Lockwood WW. Leung AW, et al. Mol Cancer. 2016 Sep 29;15(1):61. doi: 10.1186/s12943-016-0546-y. Mol Cancer. 2016. PMID: 27686855 Free PMC article. Review.

4

Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status.

Wehbe M, Lo C, Leung AWY, Dragowska WH, Ryan GM, Bally MB. Wehbe M, et al. Invest New Drugs. 2017 Dec;35(6):682-690. doi: 10.1007/s10637-017-0488-2. Epub 2017 Jul 21. Invest New Drugs. 2017. PMID: 28733701 Free PMC article.

5

Copper-CX-5461: A novel liposomal formulation for a small molecule rRNA synthesis inhibitor.

Leung AWY, Anantha M, Dragowska WH, Wehbe M, Bally MB. Leung AWY, et al. J Control Release. 2018 Sep 28;286:1-9. doi: 10.1016/j.jconrel.2018.07.025. Epub 2018 Jul 18. J Control Release. 2018. PMID: 30016731 Free article.

6

Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response.

Gilabert-Oriol R, Ryan GM, Leung AWY, Firmino NS, Bennewith KL, Bally MB. Gilabert-Oriol R, et al. Int J Mol Sci. 2018 Sep 26;19(10):2922. doi: 10.3390/ijms19102922. Int J Mol Sci. 2018. PMID: 30261606 Free PMC article. Review.

7

Recent Treatment Advances and the Role of Nanotechnology, Combination Products, and Immunotherapy in Changing the Therapeutic Landscape of Acute Myeloid Leukemia.

Chen KTJ, Gilabert-Oriol R, Bally MB, Leung AWY. Chen KTJ, et al. Pharm Res. 2019 Jun 24;36(9):125. doi: 10.1007/s11095-019-2654-z. Pharm Res. 2019. PMID: 31236772 Free PMC article. Review.

8

In Vivo Validation of PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) as a Cisplatin-sensitizing Therapeutic Target.

Leung AWY, Veinotte CJ, Melong N, Oh MH, Chen K, Enfield KSS, Backstrom I, Warburton C, Yapp D, Berman JN, Bally MB, Lockwood WW. Leung AWY, et al. Clin Cancer Res. 2017 Nov 1;23(21):6555-6566. doi: 10.1158/1078-0432.CCR-17-0700. Epub 2017 Aug 8. Clin Cancer Res. 2017. PMID: 28790117

9

Nanoscale Reaction Vessels Designed for Synthesis of Copper-Drug Complexes Suitable for Preclinical Development.

Wehbe M, Anantha M, Backstrom I, Leung A, Chen K, Malhotra A, Edwards K, Bally MB. Wehbe M, et al. PLoS One. 2016 Apr 7;11(4):e0153416. doi: 10.1371/journal.pone.0153416. eCollection 2016. PLoS One. 2016. PMID: 27055237 Free PMC article.

10

Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell Lung Cancer Cells In Vitro.

Leung AW, Hung SS, Backstrom I, Ricaurte D, Kwok B, Poon S, McKinney S, Segovia R, Rawji J, Qadir MA, Aparicio S, Stirling PC, Steidl C, Bally MB. Leung AW, et al. PLoS One. 2016 Mar 3;11(3):e0150675. doi: 10.1371/journal.pone.0150675. eCollection 2016. PLoS One. 2016. PMID: 26938915 Free PMC article.

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