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Phase I dose finding studies of obatoclax (GX15-070), a small molecule pan-BCL-2 family antagonist, in patients with advanced solid tumors or lymphoma.
Hwang JJ, Kuruvilla J, Mendelson D, Pishvaian MJ, Deeken JF, Siu LL, Berger MS, Viallet J, Marshall JL. Hwang JJ, et al. Among authors: kuruvilla j. Clin Cancer Res. 2010 Aug 1;16(15):4038-45. doi: 10.1158/1078-0432.CCR-10-0822. Epub 2010 Jun 10. Clin Cancer Res. 2010. PMID: 20538761 Free PMC article. Clinical Trial.
Selective inhibition of nuclear export with selinexor in patients with non-Hodgkin lymphoma.
Kuruvilla J, Savona M, Baz R, Mau-Sorensen PM, Gabrail N, Garzon R, Stone R, Wang M, Savoie L, Martin P, Flinn I, Jacoby M, Unger TJ, Saint-Martin JR, Rashal T, Friedlander S, Carlson R, Kauffman M, Shacham S, Gutierrez M. Kuruvilla J, et al. Blood. 2017 Jun 15;129(24):3175-3183. doi: 10.1182/blood-2016-11-750174. Epub 2017 May 3. Blood. 2017. PMID: 28468797 Free article. Clinical Trial.
Similar response rates and superior early progression-free survival with gemcitabine, dexamethasone, and cisplatin salvage therapy compared with carmustine, etoposide, cytarabine, and melphalan salvage therapy prior to autologous stem cell transplantation for recurrent or refractory Hodgkin lymphoma.
Kuruvilla J, Nagy T, Pintilie M, Tsang R, Keating A, Crump M. Kuruvilla J, et al. Cancer. 2006 Jan 15;106(2):353-60. doi: 10.1002/cncr.21587. Cancer. 2006. PMID: 16329112 Free article.
Relapsed and refractory aggressive NHL: time for a change.
Gangatharan S, Kuruvilla J. Gangatharan S, et al. Among authors: kuruvilla j. Transfus Apher Sci. 2013 Aug;49(1):72-9. doi: 10.1016/j.transci.2013.05.029. Epub 2013 Jul 5. Transfus Apher Sci. 2013. PMID: 23835116 Review.
254 results