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Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein.
Bioorg Med Chem Lett. 2014 May 15;24(10):2288-94. doi: 10.1016/j.bmcl.2014.03.080. Epub 2014 Apr 3.
Bioorg Med Chem Lett. 2014.
PMID: 24731273
Hepatitis C replication inhibitors that target the viral NS4B protein.
Miller JF, Chong PY, Shotwell JB, Catalano JG, Tai VW, Fang J, Banka AL, Roberts CD, Youngman M, Zhang H, Xiong Z, Mathis A, Pouliot JJ, Hamatake RK, Price DJ, Seal JW 3rd, Stroup LL, Creech KL, Carballo LH, Todd D, Spaltenstein A, Furst S, Hong Z, Peat AJ.
Miller JF, et al. Among authors: seal jw 3rd.
J Med Chem. 2014 Mar 13;57(5):2107-20. doi: 10.1021/jm400125h. Epub 2013 Apr 19.
J Med Chem. 2014.
PMID: 23544424
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Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization.
Shotwell JB, Baskaran S, Chong P, Creech KL, Crosby RM, Dickson H, Fang J, Garrido D, Mathis A, Maung J, Parks DJ, Pouliot JJ, Price DJ, Rai R, Seal JW 3rd, Schmitz U, Tai VW, Thomson M, Xie M, Xiong ZZ, Peat AJ.
Shotwell JB, et al. Among authors: seal jw 3rd.
ACS Med Chem Lett. 2012 May 24;3(7):565-9. doi: 10.1021/ml300090x. eCollection 2012 Jul 12.
ACS Med Chem Lett. 2012.
PMID: 24900511
Free PMC article.
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