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Mapping the cellular response to small molecules using chemogenomic fitness signatures.
Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, Suresh S, Duby G, Heisler LE, Surendra A, Fung E, Urbanus ML, Gebbia M, Lissina E, Miranda M, Chiang JH, Aparicio AM, Zeghouf M, Davis RW, Cherfils J, Boutry M, Kaiser CA, Cummins CL, Trimble WS, Brown GW, Schimmer AD, Bankaitis VA, Nislow C, Bader GD, Giaever G. Lee AY, et al. Among authors: cummins cl. Science. 2014 Apr 11;344(6180):208-11. doi: 10.1126/science.1250217. Science. 2014. PMID: 24723613 Free PMC article.
ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development.
Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, Hughes TR, Morris QD, Scott MS, Krause H, Angers S, Blencowe BJ, Cummins CL. Magomedova L, et al. Among authors: cummins cl. Nucleic Acids Res. 2019 Apr 8;47(6):2856-2870. doi: 10.1093/nar/gkz010. Nucleic Acids Res. 2019. PMID: 30698747 Free PMC article.
Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.
Dotan I, Yang J, Ikeda J, Roth Z, Pollock-Tahiri E, Desai H, Sivasubramaniyam T, Rehal S, Rapps J, Li YZ, Le H, Farber G, Alchami E, Xiao C, Karim S, Gronda M, Saikali MF, Tirosh A, Wagner KU, Genest J, Schimmer AD, Gupta V, Minden MD, Cummins CL, Lewis GF, Robbins C, Jongstra-Bilen J, Cybulsky M, Woo M. Dotan I, et al. Among authors: cummins cl. Commun Biol. 2022 Feb 15;5(1):132. doi: 10.1038/s42003-022-03078-5. Commun Biol. 2022. PMID: 35169231 Free PMC article.
Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors.
Han H, Braunschweig U, Gonatopoulos-Pournatzis T, Weatheritt RJ, Hirsch CL, Ha KCH, Radovani E, Nabeel-Shah S, Sterne-Weiler T, Wang J, O'Hanlon D, Pan Q, Ray D, Zheng H, Vizeacoumar F, Datti A, Magomedova L, Cummins CL, Hughes TR, Greenblatt JF, Wrana JL, Moffat J, Blencowe BJ. Han H, et al. Among authors: cummins cl. Mol Cell. 2017 Feb 2;65(3):539-553.e7. doi: 10.1016/j.molcel.2017.01.011. Mol Cell. 2017. PMID: 28157508 Free article.
Exploring the transformability of polymer-lipid hybrid nanoparticles and nanomaterial-biology interplay to facilitate tumor penetration, cellular uptake and intracellular targeting of anticancer drugs.
Amini MA, Ahmed T, Liu FF, Abbasi AZ, Soeandy CD, Zhang RX, Prashad P, Cummins CL, Rauth AM, Henderson JT, Wu XY. Amini MA, et al. Among authors: cummins cl. Expert Opin Drug Deliv. 2021 Jul;18(7):991-1004. doi: 10.1080/17425247.2021.1902984. Epub 2021 Mar 30. Expert Opin Drug Deliv. 2021. PMID: 33703991
89 results